56632-83-8
56632-83-8 structure
- Name: 2'-Fluoro-2'-deoxy-arabinofuranosyl-cytidine
- Chemical Name: 4-amino-1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
- CAS Number: 56632-83-8
- Molecular Formula: C9H12FN3O4
- Molecular Weight: 245.21
- Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
- Create Date: 2018-11-23 08:13:59
- Modify Date: 2026-08-21 21:13:05
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2’-Deoxy-2’-fluoro-b-D-arabinocytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
| Name | 4-amino-1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one |
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| Synonyms |
4-Amino-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-2(1H)-pyrimidinone
1-(2'-Deoxy-2'-fluoro-b-D-abinofuranosyl)cytosine Hydrochloride 1-(2'-Deoxy-2'-fluoro-b-D-abinofuranosyl)cytosine 2’-Deoxy-2’-fluoro-beta-D-abinocytidine, FAC, anticancer,metabolite of FIAC (GL100674), impurity of Azvudine 2’-Deoxy-2’-fluoro--D-abino cytidine 1-(2'-Deoxy-2'-fluoro-b-D-abinofuranosyl)cytosine HCl 2'-FANA-cytidine 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-cytosine 1-(2-Deoxy-2-fluoro-beta-D-abinofuranosyl)cytosine 4-Amino-1-(2-deoxy-2-fluoro-D-abinofuranosyl)-2(1H)-pyrimidinone 4-Amino-1-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)pyriMidin-2(1H)-one FN-008 2'-Fluoro-2'-deoxy-abinofuranosyl-cytidine 2(1H)-Pyrimidinone, 4-amino-1-(2-deoxy-2-fluoro-β-D-abinofuranosyl) 2'-Fluoro-2'-deoxy-abinofuranosyl-cytidine 2'-Deoxy-2'-fluoro-beta-D-abinocytidine 4-Amino-1-(2-deoxy-2-fluoro-β-D-abinofuranosyl)-2(1H)-pyrimidinone 2’-Deoxy-2’-fluoro-beta-D-abinocytidine, FAC 2’-Deoxy-2’-fluoro-beta-D-abinocytidine 2'-Fluoro-2'-deoxy-abino-Cytidine 4-Amino-1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-2(1H)-pyrimidinone 2'deoxy-2'-fluoroarabinocytidine 4-Amino-1-(2-deoxy-2-fluoro-beta-D-abinofuranosyl)-2(1H)-pyrimidinone Eravacycline Impurity 10 2’-Deoxy-2’-fluoro-β-D-abinocytidine 4-Amino-1-(2-deoxy-2-fluoro-beta-D-abinofuranosyl)-2(1H)-p 2’-Deoxy-2’-fluoro-b-D-abinocytidine 4-Amino-1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)pyrimidin-2(1H)-one |
| Description | 2’-Deoxy-2’-fluoro-b-D-arabinocytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | |
| References |
| Density | 1.8±0.1 g/cm3 |
|---|---|
| Boiling Point | 500.1±60.0 °C at 760 mmHg |
| Molecular Formula | C9H12FN3O4 |
| Molecular Weight | 245.21 |
| Flash Point | 256.2±32.9 °C |
| Exact Mass | 245.081177 |
| PSA | 110.60000 |
| LogP | -1.26 |
| Vapour Pressure | 0.0±2.9 mmHg at 25°C |
| Index of Refraction | 1.697 |
| Precursor 3 | |
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| DownStream 1 | |
![4-amino-5-ethyl-1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one structure](https://image.chemsrc.com/caspic/398/95740-17-3.png)