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Product Name: 4,4'-(1-acetyl-2-oxoindolin-3-ylidene)diphenyl di(acetate)
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18869-73-3

18869-73-3 structure

18869-73-3 structure

Name: 4,4'-(1-acetyl-2-oxoindolin-3-ylidene)diphenyl di(acetate)
Chemical Name: [4-[1-acetyl-3-(4-acetyloxyphenyl)-2-oxoindol-3-yl]phenyl] acetate
CAS Number: 18869-73-3
Molecular Formula: C₂₆H₂₁NO₆
Molecular Weight: 443.44800
Create Date: 2016-08-14 04:51:39
Modify Date: 2024-09-16 19:07:17

Name	[4-[1-acetyl-3-(4-acetyloxyphenyl)-2-oxoindol-3-yl]phenyl] acetate
Synonyms	Laxagen Phenisatin Isatex Laxagetten EINECS 242-638-4 3,3-bis-(4-acetoxy-phenyl)-1-acetyl-indolin-2-one Triacetyldiphenolisatin Neo-Hollaxans 4,4'-(1-acetyl-2-oxoindolin-3-ylidene)diphenyl di(acetate) Trialax Dissilax-Zaepfchen Trisatin

Density	1.306g/cm3
Boiling Point	623.6ºC at 760 mmHg
Molecular Formula	C₂₆H₂₁NO₆
Molecular Weight	443.44800
Flash Point	331ºC
Exact Mass	443.13700
PSA	89.98000
LogP	3.82970
Vapour Pressure	1.79E-15mmHg at 25°C
Index of Refraction	1.613

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NM3250000

CHEMICAL NAME :: 2H-Indol-2-one, 1,3-dihydro-1-acetyl-3,3-bis(4-(acetyloxy)phenyl)-

CAS REGISTRY NUMBER :: 18869-73-3

BEILSTEIN REFERENCE NO. :: 0365442

LAST UPDATED :: 199710

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C26-H21-N-O6

MOLECULAR WEIGHT :: 443.48

WISWESSER LINE NOTATION :: T56 BNV DHJ BV1 DR DOV1& DOV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 42,468,1953

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 350 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 42,468,1953 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 90 mg/kg/30D-C

TOXIC EFFECTS :: Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death

REFERENCE :: JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 42,468,1953

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 5460 mg/kg/1Y-C

TOXIC EFFECTS :: Gastrointestinal - hypermotility, diarrhea

REFERENCE :: JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 42,468,1953

HS Code	2933790090

108-24-7 structure

108-24-7

~%

18869-73-3 structure

18869-73-3

Literature: Liebermann; Danaila Chemische Berichte, 1907 , vol. 40, p. 3592

Precursor 1
108-24-7
DownStream 0

HS Code	2933790090
Summary	2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

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