494-79-1
494-79-1 structure
- Name: melarsoprol
- Chemical Name: [2-[4-[(4,6-diamino-1,3,5-triazin-2-yl)amino]phenyl]-1,3,2-dithiarsolan-4-yl]methanol
- CAS Number: 494-79-1
- Molecular Formula: C12H15AsN6OS2
- Molecular Weight: 398.33900
- Catalog: Research Areas Infection
- Create Date: 2018-02-10 08:00:00
- Modify Date: 2026-07-14 10:19:19
-
Melarsoprol (Arsobal), a melaminophenylarsine-type trivalent organic arsenical, is an important drug for African trypanosomiasis. Melarsoprol is also active against leukemia cell lines and plasma cells from myeloma patients. Melarsoprol increases the biliary output of GSH in rats[1].
| Name | [2-[4-[(4,6-diamino-1,3,5-triazin-2-yl)amino]phenyl]-1,3,2-dithiarsolan-4-yl]methanol |
|---|---|
| Synonyms |
[2-[4-[(4,6-diamino-1,3,5-triazin-2-yl)amino]phenyl]-1,3,2-dithisolan-4-yl]methanol
Melsoprol (Mixture of DiastereoMers) Melarsoprolum melsoprol Arsobal 2-[4-[(4,6-Diamino-1,3,5-triazin-2-yl)amino]phenyl]-1,3,2-dithisolane-4-methanol Melarsoprol Melarsoprolum [INN-Latin] Melarsenoxid-BAL 2-[4-(4,6-Diamino-1,3,5-triazine-2-ylamino)phenyl]-1,3,2-dithisolane-4-methanol {2-[4-(4,6-diamino-[1,3,5]triazin-2-ylamino)-phenyl]-[1,3,2]dithiarsolan-4-yl}-methanol 1,3,2-Dithisolane-4-methanol, 2-[4-[(4,6-diamino-1,3,5-triazin-2-yl)amino]phenyl] RP3854 2-(p-(4,6-Diamino-s-triazin-2-ylamino)phenyl)-1,3,2-dithiarsolane-4-methanol melarsenoxide-BAL [2-[4-[(4,6-diamino-s-triazin-2-yl)amino]phenyl]-1,3,2-dithisolan-4-yl]methanol Melsoprolum 1,3,2-Dithiarsolane-4-methanol,2-(4-((4,6-diamino-1,3,5-triazin-2-yl)amino)phenyl) sobal Mel B EINECS 207-793-4 [2-[4-[[4,6-bis(azanyl)-1,3,5-triazin-2-yl]amino]phenyl]-1,3,2-dithisolan-4-yl]methanol |
| Description | Melarsoprol (Arsobal), a melaminophenylarsine-type trivalent organic arsenical, is an important drug for African trypanosomiasis. Melarsoprol is also active against leukemia cell lines and plasma cells from myeloma patients. Melarsoprol increases the biliary output of GSH in rats[1]. |
|---|---|
| Related Catalog | |
| References |
| Boiling Point | 688.4ºC at 760 mmHg |
|---|---|
| Molecular Formula | C12H15AsN6OS2 |
| Molecular Weight | 398.33900 |
| Flash Point | 370.2ºC |
| Exact Mass | 397.99600 |
| PSA | 173.57000 |
| LogP | 1.55110 |
| Vapour Pressure | 6.7E-20mmHg at 25°C |
|
~%
494-79-1 |
| Literature: Gibaud, Stephane; Alfonsi, Raphael; Mutzenhardt, Pierre; Fries, Isabelle; Astier, Alain Journal of Organometallic Chemistry, 2006 , vol. 691, # 5 p. 1081 - 1084 |
| Precursor 1 | |
|---|---|
| DownStream 0 | |