26308-28-1

26308-28-1 structure
26308-28-1 structure
  • Name: Ripazepam
  • Chemical Name: 1-ethyl-3-methyl-8-phenyl-4,6-dihydropyrazolo[4,3-e][1,4]diazepin-5-one
  • CAS Number: 26308-28-1
  • Molecular Formula: C15H16N4O
  • Molecular Weight: 268.31400
  • Catalog: Research Areas Neurological Disease
  • Create Date: 2018-09-09 19:24:01
  • Modify Date: 2024-01-11 14:43:06
  • Ripazepam (Cl-683) is a potential antianxiety agent. Ripazepam also is a pyrazolodiazepinone derivative and has anxiolytic effects[1].

Name 1-ethyl-3-methyl-8-phenyl-4,6-dihydropyrazolo[4,3-e][1,4]diazepin-5-one
Synonyms 1-ethyl-3-methyl-8-phenyl-4,6-dihydro-1H-pyrazolo[4,3-e][1,4]diazepin-5-one
Ripazepamum [INN-Latin]
RIPAZEPAM
1-Ethyl-1,4,5,6-tetrahydro-3-methyl-8-phenylpyrazolo(4,3-e)(1,4)diazepin-5-on
CI-683
Cl-683
Pyrazapon
Ripazepam [USAN:INN]
Description Ripazepam (Cl-683) is a potential antianxiety agent. Ripazepam also is a pyrazolodiazepinone derivative and has anxiolytic effects[1].
Related Catalog
Density 1.28g/cm3
Boiling Point 466.6ºC at 760 mmHg
Molecular Formula C15H16N4O
Molecular Weight 268.31400
Flash Point 236ºC
Exact Mass 268.13200
PSA 59.28000
LogP 1.57450
Vapour Pressure 6.97E-09mmHg at 25°C
Index of Refraction 1.664

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UR0100000
CHEMICAL NAME :
Pyrazolo(4,3-e)(1,4)diazepin-5(1H)-one, 4,6-dihydro-1-ethyl-3-methyl-8-phenyl-
CAS REGISTRY NUMBER :
26308-28-1
LAST UPDATED :
199703
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C15-H16-N4-O
MOLECULAR WEIGHT :
268.35

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
81900 mg/kg/78W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Liver - tumors
REFERENCE :
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 4,178,1984 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 66,157,1996 IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 66,157,1996 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 66,157,1996
RIDADR UN 3249
Packaging Group III
Hazard Class 6.1(b)
HS Code 2933990090
HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%