106916-16-9

106916-16-9 structure
106916-16-9 structure
  • Name: 4-(2-(PROPYLAMINO)ETHYL)INDOLIN-2-ONE
  • Chemical Name: N-Despropyl Ropinirole
  • CAS Number: 106916-16-9
  • Molecular Formula: C13H18N2O
  • Molecular Weight: 218.29
  • Catalog: Signaling Pathways GPCR/G Protein Dopamine Receptor
  • Create Date: 2019-02-02 11:36:29
  • Modify Date: 2024-01-02 11:03:59
  • N-Despropyl Ropinirole (SKF-104557) is an active metabolite of the dopamine D2 receptor agonist Ropinirole (HY-B0623). N-Despropyl Ropinirole is a full agonist at human D2 and D3 receptors. N-Despropyl Ropinirole is a partial agonistof the hD4 receptor[1].

Name N-Despropyl Ropinirole
Synonyms 2H-Indol-2-one, 1,3-dihydro-4-[2-(propylamino)ethyl]-
4-[2-(propylamino)ethyl]-1,3-dihydroindol-2-one
4-[2-(Propylamino)ethyl]-1,3-dihydro-2H-indol-2-one
4-(2-(Propylamino)ethyl)indolin-2-one
Description N-Despropyl Ropinirole (SKF-104557) is an active metabolite of the dopamine D2 receptor agonist Ropinirole (HY-B0623). N-Despropyl Ropinirole is a full agonist at human D2 and D3 receptors. N-Despropyl Ropinirole is a partial agonistof the hD4 receptor[1].
Related Catalog
References

[1]. Coldwell MC, et al. Comparison of the functional potencies of ropinirole and other dopamine receptor agonists at human D2(long), D3 and D4.4 receptors expressed in Chinese hamster ovary cells. Br J Pharmacol. 1999 Aug;127(7):1696-702.  

Density 1.1±0.1 g/cm3
Boiling Point 387.7±42.0 °C at 760 mmHg
Melting Point 260-265ºC
Molecular Formula C13H18N2O
Molecular Weight 218.29
Flash Point 154.2±28.0 °C
Exact Mass 218.141907
PSA 41.13000
LogP 1.59
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.549
HS Code 2933790090
HS Code 2933790090
Summary 2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%