153365-82-3

153365-82-3 structure

Name: THREO-DIHYDROBUPROPION
Chemical Name: threo-dihydrobupropion
CAS Number: 153365-82-3
Molecular Formula: C₁₃H₂₀ClNO
Molecular Weight: 241.75700
Catalog: Research Areas Neurological Disease
Create Date: 2017-02-01 12:56:46
Modify Date: 2024-01-10 17:45:11
Threo-dihydrobupropion is a major metabolite of Bupropion, formed via oxidation and reduction exhibit pharmacological activity. Bupropion, a dual dopamine-norepinephrine uptake inhibitor and a nicotine receptor antagonist, is widely used in the management of depression and as a smoking cessation aid[1].

Name	threo-dihydrobupropion
Synonyms	(R,R)-2-(T-BUTYLAMINO)1-(3-CHLOROPHENYL) PROPANOL MALEATE (R,R)-2-(T-BUTYLAMINO)1-(3-CHLOROPHENYL) PROPANOL threo-Hydroxy Bupropion HCl THREO-HYDROBUPROPION

Description	Threo-dihydrobupropion is a major metabolite of Bupropion, formed via oxidation and reduction exhibit pharmacological activity. Bupropion, a dual dopamine-norepinephrine uptake inhibitor and a nicotine receptor antagonist, is widely used in the management of depression and as a smoking cessation aid[1].
Related Catalog	Research Areas >> Neurological Disease
References	[1]. Andrea R Masters, et al. Stereoselective method to quantify bupropion and its three major metabolites, hydroxybupropion, erythro-dihydrobupropion, and threo-dihydrobupropion using HPLC-MS/MS. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Mar 15;1015-1016:201-208.