CHEMICAL IDENTIFICATION
-
RTECS NUMBER :
-
DP1230000
-
CHEMICAL NAME :
-
Benzyl alcohol, alpha-((2-pyrimidinylamino)methyl)-, monohydrochloride
-
CAS REGISTRY NUMBER :
-
2441-88-5
-
LAST UPDATED :
-
199503
-
DATA ITEMS CITED :
-
6
-
MOLECULAR FORMULA :
-
C12-H13-N3-O.Cl-H
-
MOLECULAR WEIGHT :
-
251.74
-
WISWESSER LINE NOTATION :
-
T6N CNJ BM1YQR &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
-
TYPE OF TEST :
-
LD50 - Lethal dose, 50 percent kill
-
ROUTE OF EXPOSURE :
-
Intraperitoneal
-
SPECIES OBSERVED :
-
Rodent - rat
-
DOSE/DURATION :
-
235 mg/kg
-
TOXIC EFFECTS :
-
Lungs, Thorax, or Respiration - other changes
-
REFERENCE :
-
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 141,83,1963
-
TYPE OF TEST :
-
LD50 - Lethal dose, 50 percent kill
-
ROUTE OF EXPOSURE :
-
Oral
-
SPECIES OBSERVED :
-
Rodent - mouse
-
DOSE/DURATION :
-
850 mg/kg
-
TOXIC EFFECTS :
-
Lungs, Thorax, or Respiration - other changes
-
REFERENCE :
-
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 141,83,1963
-
TYPE OF TEST :
-
LD50 - Lethal dose, 50 percent kill
-
ROUTE OF EXPOSURE :
-
Intraperitoneal
-
SPECIES OBSERVED :
-
Rodent - mouse
-
DOSE/DURATION :
-
360 mg/kg
-
TOXIC EFFECTS :
-
Behavioral - coma Cardiac - other changes Lungs, Thorax, or Respiration - other changes
-
REFERENCE :
-
AAREAV Anesthesie, Analgesie, Reanimation. (Paris, France) V.14-38, 1957-81. Volume(issue)/page/year: 22,87,1965
-
TYPE OF TEST :
-
LD50 - Lethal dose, 50 percent kill
-
ROUTE OF EXPOSURE :
-
Intravenous
-
SPECIES OBSERVED :
-
Rodent - mouse
-
DOSE/DURATION :
-
125 mg/kg
-
TOXIC EFFECTS :
-
Behavioral - coma Cardiac - other changes Lungs, Thorax, or Respiration - other changes
-
REFERENCE :
-
AAREAV Anesthesie, Analgesie, Reanimation. (Paris, France) V.14-38, 1957-81. Volume(issue)/page/year: 22,87,1965
-
TYPE OF TEST :
-
LD50 - Lethal dose, 50 percent kill
-
ROUTE OF EXPOSURE :
-
Intravenous
-
SPECIES OBSERVED :
-
Mammal - dog
-
DOSE/DURATION :
-
125 mg/kg
-
TOXIC EFFECTS :
-
Lungs, Thorax, or Respiration - other changes
-
REFERENCE :
-
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 141,83,1963
-
TYPE OF TEST :
-
LDLo - Lowest published lethal dose
-
ROUTE OF EXPOSURE :
-
Intravenous
-
SPECIES OBSERVED :
-
Rodent - rabbit
-
DOSE/DURATION :
-
350 mg/kg
-
TOXIC EFFECTS :
-
Cardiac - other changes Lungs, Thorax, or Respiration - other changes
-
REFERENCE :
-
AAREAV Anesthesie, Analgesie, Reanimation. (Paris, France) V.14-38, 1957-81. Volume(issue)/page/year: 22,87,1965
|
