35665-58-8

35665-58-8 structure

Name: 5-(6-dimethylaminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
Chemical Name: 5-[6-(dimethylamino)purin-9-yl]-2-(hydroxymethyl)oxolan-3-ol
CAS Number: 35665-58-8
Molecular Formula: C₁₂H₁₇N₅O₃
Molecular Weight: 279.30
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2016-01-02 23:43:01
Modify Date: 2024-01-29 18:21:42
N6-Dimethyldeoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	5-[6-(dimethylamino)purin-9-yl]-2-(hydroxymethyl)oxolan-3-ol
Synonyms	N6,N6-dimethyl-2'-deoxyadenosine

Description	N6-Dimethyldeoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.