166020-57-1

166020-57-1 structure

Name: BA 41899
Chemical Name: 5-methyl-6-phenyl-5,6-dihydro-3,6-methano-1,5-benzodiazocine-2,4(1H,3H)-dione
CAS Number: 166020-57-1
Molecular Formula: C₁₈H₁₆N₂O₂
Molecular Weight: 292.33200
Catalog: Research Areas Cardiovascular Disease
Create Date: 2017-09-23 03:18:25
Modify Date: 2024-01-04 20:19:29
BA 41899 is a purely calcium-sensitizing agent. BA 41899 is completely devoid of phosphodiesterase (PDE) III inhibitory activity or any other known inotropic mechanism. BA 41899 can be used for the research of cardiovascular diseases, such as congestive heart failure (CHF)[1].

Name	5-methyl-6-phenyl-5,6-dihydro-3,6-methano-1,5-benzodiazocine-2,4(1H,3H)-dione
Synonyms	5-methyl-6-phenyl-5,6-dihydro-3,6-methano-1,5-benzodiazocine-2,4(1H,3H)-dione 12-Methyl-1-phenyl-8,12-diazatricyclo[8.2.1.0]trideca-2,4,6-triene-9,11-dione 3,6-Methano-1,5-benzodiazocine-2,4(1H,3H)-dione, 5,6-dihydro-5-methyl-6-phenyl- 5-Methyl-6-phenyl-1,3,5,6-tetrahydro-3,6-methano-1,5-benzodiazocine-2,4-dione

Description	BA 41899 is a purely calcium-sensitizing agent. BA 41899 is completely devoid of phosphodiesterase (PDE) III inhibitory activity or any other known inotropic mechanism. BA 41899 can be used for the research of cardiovascular diseases, such as congestive heart failure (CHF)[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others
In Vitro	BA 41899 (compound 6) 表现出包括 Ca2+ 敏化、正性肌力和负性变时作用在内的体外药理学特性[1]。
References	[1]. Herold, P et al. 5-Methyl-6-phenyl-1,3,5,6-tetrahydro-3,6-methano-1,5-benzodiazocine-2,4-dione (BA 41899): representative of a novel class of purely calcium-sensitizing agents. Journal of medicinal chemistry vol. 38,15 (1995): 2946-54.