866823-73-6
866823-73-6 structure
- Name: Biphenylindanone A
- Chemical Name: 4-[3-[(2-cyclopentyl-6,7-dimethyl-1-oxo-2,3-dihydroinden-5-yl)oxymethyl]phenyl]benzoic acid
- CAS Number: 866823-73-6
- Molecular Formula: C30H30O4
- Molecular Weight: 454.557
- Catalog: Signaling Pathways GPCR/G Protein mGluR
- Create Date: 2018-12-28 09:32:09
- Modify Date: 2024-01-14 12:38:30
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Biphenylindanone A (BINA) is a selective human mGluR2 (hmGluR2) potentiator for the treatment of many neurological disorders[1].
| Name | 4-[3-[(2-cyclopentyl-6,7-dimethyl-1-oxo-2,3-dihydroinden-5-yl)oxymethyl]phenyl]benzoic acid |
|---|---|
| Synonyms |
LS-193,571
BINA [1,1'-Biphenyl]-4-carboxylic acid, 3'-[[(2-cyclopentyl-2,3-dihydro-6,7-dimethyl-1-oxo-1H-inden-5-yl)oxy]methyl]- 3'-{[(2-Cyclopentyl-6,7-dimethyl-1-oxo-2,3-dihydro-1H-inden-5-yl)oxy]methyl}-4-biphenylcarboxylic acid cc-230 Biphenylindanone A |
| Description | Biphenylindanone A (BINA) is a selective human mGluR2 (hmGluR2) potentiator for the treatment of many neurological disorders[1]. |
|---|---|
| Related Catalog | |
| Target |
mGluR2 |
| In Vitro | Biphenylindanone A (BINA) shows activity on glutamate-induced scintillation proximity assay [3H]IP1 hydrolysis on WT mGluR2 (EC50=1.57 μM) in the absence or presence of 5 μM glutamate[1]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 676.9±55.0 °C at 760 mmHg |
| Molecular Formula | C30H30O4 |
| Molecular Weight | 454.557 |
| Flash Point | 225.8±25.0 °C |
| Exact Mass | 454.214417 |
| PSA | 63.60000 |
| LogP | 8.27 |
| Vapour Pressure | 0.0±2.2 mmHg at 25°C |
| Index of Refraction | 1.627 |
| RIDADR | NONH for all modes of transport |
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