Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Biphenylindanone A
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

ShangHai DC Chemicals Co.,Ltd
China
Product Name: Biphenylindanone A
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Lai

DC Chemicals Limited
China
Product Name: Biphenylindanone A
Price: $980.0/100mg $1600.0/250mg $3300.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Biphenylindanone A
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

866823-73-6

866823-73-6 structure

866823-73-6 structure

Name: Biphenylindanone A
Chemical Name: 4-[3-[(2-cyclopentyl-6,7-dimethyl-1-oxo-2,3-dihydroinden-5-yl)oxymethyl]phenyl]benzoic acid
CAS Number: 866823-73-6
Molecular Formula: C₃₀H₃₀O₄
Molecular Weight: 454.557
Catalog: Signaling Pathways GPCR/G Protein mGluR
Create Date: 2018-12-28 09:32:09
Modify Date: 2024-01-14 12:38:30
Biphenylindanone A (BINA) is a selective human mGluR2 (hmGluR2) potentiator for the treatment of many neurological disorders[1].

Name	4-[3-[(2-cyclopentyl-6,7-dimethyl-1-oxo-2,3-dihydroinden-5-yl)oxymethyl]phenyl]benzoic acid
Synonyms	LS-193,571 BINA [1,1'-Biphenyl]-4-carboxylic acid, 3'-[[(2-cyclopentyl-2,3-dihydro-6,7-dimethyl-1-oxo-1H-inden-5-yl)oxy]methyl]- 3'-{[(2-Cyclopentyl-6,7-dimethyl-1-oxo-2,3-dihydro-1H-inden-5-yl)oxy]methyl}-4-biphenylcarboxylic acid cc-230 Biphenylindanone A

Description	Biphenylindanone A (BINA) is a selective human mGluR2 (hmGluR2) potentiator for the treatment of many neurological disorders[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> mGluR Research Areas >> Neurological Disease
Target	mGluR2
In Vitro	Biphenylindanone A (BINA) shows activity on glutamate-induced scintillation proximity assay [3H]IP1 hydrolysis on WT mGluR2 (EC50=1.57 μM) in the absence or presence of 5 μM glutamate[1].
References	[1]. Rowe BA, et al. Transposition of three amino acids transforms the human metabotropic glutamate receptor (mGluR)-3-positive allosteric modulation site to mGluR2, and additional characterization of the mGluR2-positive allosteric modulation site. J Pharmacol Exp Ther. 2008 Jul;326(1):240-51.

Density	1.2±0.1 g/cm3
Boiling Point	676.9±55.0 °C at 760 mmHg
Molecular Formula	C₃₀H₃₀O₄
Molecular Weight	454.557
Flash Point	225.8±25.0 °C
Exact Mass	454.214417
PSA	63.60000
LogP	8.27
Vapour Pressure	0.0±2.2 mmHg at 25°C
Index of Refraction	1.627

RIDADR	NONH for all modes of transport