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1274859-33-4

1274859-33-4 structure
1274859-33-4 structure
  • Name: VU 0360223
  • Chemical Name: vu 0360223
  • CAS Number: 1274859-33-4
  • Molecular Formula: C15H9FN2S
  • Molecular Weight: 268.309
  • Catalog: Signaling Pathways GPCR/G Protein mGluR
  • Create Date: 2016-05-07 09:43:13
  • Modify Date: 2024-01-07 12:37:34
  • VU 0360223 is a potent metabotropic glutamate receptors (mGluR) negative allosteric modulator with an IC50 of 61 nM[1].

Name vu 0360223
Synonyms Benzonitrile, 3-fluoro-5-(2-methyl-5-benzothiazolyl)-
3-Fluoro-5-(2-methyl-1,3-benzothiazol-5-yl)benzonitrile
Description VU 0360223 is a potent metabotropic glutamate receptors (mGluR) negative allosteric modulator with an IC50 of 61 nM[1].
Related Catalog
Target

mGluR:61 nM (IC50)

References

[1]. Pomierny-Chamioło L, et al. Metabotropic glutamatergic receptors and their ligands in drug addiction. Pharmacol Ther. 2014 Jun;142(3):281-305.

Density 1.4±0.1 g/cm3
Boiling Point 434.9±35.0 °C at 760 mmHg
Molecular Formula C15H9FN2S
Molecular Weight 268.309
Flash Point 216.8±25.9 °C
Exact Mass 268.047058
PSA 64.92000
LogP 4.02
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.676