135383-64-1

135383-64-1 structure

Name: clathrodin
Chemical Name: N-[(E)-3-(2-amino-1H-imidazol-5-yl)prop-2-enyl]-1H-pyrrole-2-carboxamide
CAS Number: 135383-64-1
Molecular Formula: C₁₁H₁₃N₅O
Molecular Weight: 231.25400
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Sodium Channel
Create Date: 2016-05-22 10:58:52
Modify Date: 2025-08-31 14:24:50
Clathrodin is a marine alkaloid that can be isolated from sponges of the genus, Agelas. Clathrodin is a modulator of voltage-gated sodium (NaV) channels. Clathrodin is a sodium channel neurotoxin influencing sodium channel ionic conductance[1][2].

Name	N-[(E)-3-(2-amino-1H-imidazol-5-yl)prop-2-enyl]-1H-pyrrole-2-carboxamide
Synonyms	Clathrodine Clathrodin N-(3-(2-Imino-2,3-dihydro-1H-imidazol-4-yl)-2-propenyl)-1H-pyrrole-2-carboxamide 1H-Pyrrole-2-carboxamide,N-(3-(2-amino-1H-imidazol-4-yl)-2-propenyl)-,(E)

Description	Clathrodin is a marine alkaloid that can be isolated from sponges of the genus, Agelas. Clathrodin is a modulator of voltage-gated sodium (NaV) channels. Clathrodin is a sodium channel neurotoxin influencing sodium channel ionic conductance[1][2].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel Research Areas >> Neurological Disease
References	[1]. Rentas AL, et al. Effect of alkaloid toxins from tropical marine sponges on membrane sodium currents. Toxicon. 1995 Apr;33(4):491-7.