152886-85-6

152886-85-6 structure

Name: U91356
Chemical Name: 5-(Propylamino)-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one
CAS Number: 152886-85-6
Molecular Formula: C₁₃H₁₇N₃O
Molecular Weight: 231.294
Catalog: Signaling Pathways GPCR/G Protein Dopamine Receptor
Create Date: 2017-12-23 01:54:06
Modify Date: 2024-01-12 00:09:14
U91356 is a dopamine receptor agonist.

Name	5-(Propylamino)-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one
Synonyms	(5R)-5-(propylamino)-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one 4H-Imidazo[4,5,1-ij]quinolin-2(1H)-one, 5,6-dihydro-5-(propylamino)- 5-(Propylamino)-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one 4H-Imidazo[4,5,1-ij]quinolin-2(1H)-one,5,6-dihydro-5-(propylamino)-,(5R) U91356

Description	U91356 is a dopamine receptor agonist.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor Research Areas >> Neurological Disease
Target	Dopamine receptor[1]
In Vivo	U91356 (U-91356) shows good dopaminergic agonist activity, and has good metabolic stability and oral bioavailability in the rat and monkey[2].
References	[1]. Kreiss DS, et al. Dopamine receptor agonist potencies for inhibition of cell firing correlate with dopamine D3receptor binding affinities. Eur J Pharmacol. 1995 Apr 24;277(2-3):209-14. [2]. Moon MW, et al. Medicinal chemistry of imidazoquinolinone dopamine receptor agonists. Drug Des Discov. 1993;9(3-4):313-22.