6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine

Modify Date: 2024-04-03 14:01:24

6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine Structure
6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine structure
 Common Name 6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine
CAS Number 100644-69-7 Molecular Weight 281.27
Density N/A Boiling Point N/A
Molecular Formula C11H15N5O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine


6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects[1].

 Names

Name 6-amino-1-[2'-deoxy-β-D-erythro-pentofuranosyl]-4-methoxy-1H-pyrazolo[3,4-d]pyrimidine
Synonym More Synonyms

  Biological Activity

Description 6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects[1].
Related Catalog
References

[1]. Galmarini CM, et al. Pyrimidine nucleoside analogs in cancer treatment. Expert Rev Anticancer Ther. 2003 Oct;3(5):717-28.  

 Chemical & Physical Properties

Molecular Formula C11H15N5O4
Molecular Weight 281.27
Exact Mass 281.11200
PSA 128.54000

 Synthetic Route

6-amino-1-[2'-deoxy-3',5'-di-O-(p-toluoyl)-β-D-erythro-pentofuranosyl]-4-methoxy-1H-pyrazolo[3,4-d]pyrimidine structure

6-amino-1-[2'-d...

CAS#:100644-68-6

~72%

6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine Structure

6-Amino-4-metho...

CAS#:100644-69-7

Literature: Seela; Steker Helvetica Chimica Acta, 1986 ,  vol. 69,  # 7  p. 1602 - 1613
Sodium Methylate structure

Sodium Methylate

CAS#:124-41-4

6-amino-1-[2'-deoxy-3',5'-di-O-(p-toluoyl)-β-D-erythro-pentofuranosyl]-4-methoxy-1H-pyrazolo[3,4-d]pyrimidine structure

6-amino-1-[2'-d...

CAS#:100644-68-6

~71%

6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine Structure

6-Amino-4-metho...

CAS#:100644-69-7

Literature: Seela, Frank; Steker, Herbert Heterocycles, 1985 ,  vol. 23,  # 10  p. 2521 - 2524

 Synonyms

8-aza-7-deaza-2'-deoxy-O-methylguanosine
6-Amino-1-(2'-deoxy-β-D-erythro-pentofuranosyl)-4-methoxy-1H-pyrazolo<3,4-d>pyrimidine
6-amino-1-(2'-deoxy-β-D-erythro-pentofuranosyl)-4-methoxy-1H-pyrazolo[3,4-d]pyrimidine
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Chemsrc provides CAS#:100644-69-7 MSDS, density, melting point, boiling point, structure, etc. Its name is 6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine>> amp version: 6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine

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