Fumaric acid-13c2,2h2

Modify Date: 2024-04-08 19:12:10

Fumaric acid-13c2,2h2 structure	Common Name	Fumaric acid-13c2,2h2
	CAS Number	100858-52-4	Molecular Weight	120.07
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁₃C₂H₂D₂O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Fumaric acid-13c2,2h2

Fumaric acid-13C2,d2 is the deuterium and 13C labeled Fumaric acid[1]. Fumaric acid, associated with fumarase deficiency, is identified as an oncometabolite or an endogenous, cancer causing metabolite[2].

Name	Fumaric acid-13c2,2h2

Description	Fumaric acid-13C2,d2 is the deuterium and 13C labeled Fumaric acid[1]. Fumaric acid, associated with fumarase deficiency, is identified as an oncometabolite or an endogenous, cancer causing metabolite[2].
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Whelan DT, et al. Fumaric aciduria: a new organic aciduria, associated with mental retardation and speech impairment. Clin Chim Acta. 1983 Aug 31;132(3):301-8.

Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

[2]. Whelan DT, et al. Fumaric aciduria: a new organic aciduria, associated with mental retardation and speech impairment. Clin Chim Acta. 1983 Aug 31;132(3):301-8.

Molecular Formula	C₂₁₃C₂H₂D₂O₄
Molecular Weight	120.07

Fumaric acid-13c2,2h2

Use of Fumaric acid-13c2,2h2

Names

Fumaric acid-13c2,2h2 Biological Activity

Chemical & Physical Properties