IDX899
Modify Date: 2025-09-08 09:56:49
IDX899 structure
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Common Name | IDX899 | ||
|---|---|---|---|---|
| CAS Number | 1018450-26-4 | Molecular Weight | 413.79 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 686.4±65.0 °C at 760 mmHg | |
| Molecular Formula | C20H17ClN3O3P | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 368.9±34.3 °C | |
Use of IDX899Fosdevirine (GSK2248761) is is a potent, selective, non-nucleoside reverse transcriptase inhibitor (NNRTI) of human immunodeficiency virus type 1 (HIV-1) replication with low nanomolar activity in vitro. Fosdevirine shows good activity against a broad range of HIV-1 strains, including efavirenz (HY-10572)-resistant clinical isolates[1]. |
| Name | fosdevirine |
|---|---|
| Synonym | More Synonyms |
| Description | Fosdevirine (GSK2248761) is is a potent, selective, non-nucleoside reverse transcriptase inhibitor (NNRTI) of human immunodeficiency virus type 1 (HIV-1) replication with low nanomolar activity in vitro. Fosdevirine shows good activity against a broad range of HIV-1 strains, including efavirenz (HY-10572)-resistant clinical isolates[1]. |
|---|---|
| Related Catalog | |
| Target |
HIV-1 HIV-1 (K103N) HIV-1 (Y181C) |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 686.4±65.0 °C at 760 mmHg |
| Molecular Formula | C20H17ClN3O3P |
| Molecular Weight | 413.79 |
| Flash Point | 368.9±34.3 °C |
| Exact Mass | 413.069611 |
| LogP | 2.94 |
| Vapour Pressure | 0.0±2.1 mmHg at 25°C |
| Index of Refraction | 1.664 |
| InChIKey | CGBYTKOSZYQOPV-UHFFFAOYSA-N |
| SMILES | COP(=O)(c1cc(C)cc(C=CC#N)c1)c1c(C(N)=O)[nH]c2ccc(Cl)cc12 |
| Methyl (R)-(2-carbamoyl-5-chloro-1H-indol-3-yl){3-[(E)-2-cyanovinyl]-5-methylphenyl}phosphinate |
| fosdevirine |
| Phosphinic acid, P-[2-(aminocarbonyl)-5-chloro-1H-indol-3-yl]-P-[3-[(E)-2-cyanoethenyl]-5-methylphenyl]-, methyl ester, (R)- |