3-Quinolinecarboxylic acid, 8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-7-(3-Methyl-1-piperazinyl)-4-oxo

Modify Date: 2026-08-03 16:16:10

3-Quinolinecarboxylic acid, 8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-7-(3-Methyl-1-piperazinyl)-4-oxo structure	Common Name	3-Quinolinecarboxylic acid, 8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-7-(3-Methyl-1-piperazinyl)-4-oxo
	CAS Number	101987-76-2	Molecular Weight	379.81300
	Density	1.468g/cm3	Boiling Point	598.3ºC at 760mmHg
	Molecular Formula	C₁₈H₁₉ClFN₃O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	315.7ºC

Name	8-chloro-1-cyclopropyl-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
Synonym	More Synonyms

Density	1.468g/cm3
Boiling Point	598.3ºC at 760mmHg
Molecular Formula	C₁₈H₁₉ClFN₃O₃
Molecular Weight	379.81300
Flash Point	315.7ºC
Exact Mass	379.11000
PSA	74.57000
LogP	3.01900
Vapour Pressure	3.65E-15mmHg at 25°C
Index of Refraction	1.637
InChIKey	VVDWMIBWDRTATF-UHFFFAOYSA-N
SMILES	CC1CN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2Cl)CCN1

2-Methylpiperazine

CAS#:109-07-9

8-CHLORO-1-CYCL...

CAS#:101987-89-7

~30%

3-Quinolinecarb...

CAS#:101987-76-2

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Literature: Domagala; Bridges; Culbertson; Gambino; Hagen; Karrick; Porter; Sanchez; Sesnie; Spense; Szotek; Wemple Journal of Medicinal Chemistry, 1991 , vol. 34, # 3 p. 1142 - 1154

Name: MIC ratio measured as the mean MICs of gram-negative bacteria
Source: ChEMBL
Target: N/A
External Id: CHEMBL682678

Name: Antibacterial activity was determined against gram positive organism, Streptococcus p...
Source: ChEMBL
Target: Streptococcus pneumoniae
External Id: CHEMBL799746

Name: Antibacterial activity against five Gram-positive bacteria targeting topoisomerase II...
Source: ChEMBL
Target: DNA gyrase subunit B
External Id: CHEMBL682431

Name: Antibacterial activity against five Gram-negative bacteria
Source: ChEMBL
Target: NON-PROTEIN TARGET
External Id: CHEMBL682682

Name: Antibacterial activity was determined against gram positive organism, Streptococcus f...
Source: ChEMBL
Target: Enterococcus faecalis
External Id: CHEMBL799853

Name: Minimum inhibitory concentration against Escherichia coli DNA-gyrase in supercoiling ...
Source: ChEMBL
Target: DNA gyrase subunit B
External Id: CHEMBL664852

Name: Antibacterial activity was determined against gram negative organism, Providencia ret...
Source: ChEMBL
Target: Bacteria
External Id: CHEMBL755847

Name: Antibacterial activity was determined against gram negative organism, Pseudomonas aer...
Source: ChEMBL
Target: Pseudomonas aeruginosa
External Id: CHEMBL754839

Name: Mammalian cell cytotoxicity test in chinese hamster V79 cells (clonogenic cytotoxicit...
Source: ChEMBL
Target: V79
External Id: CHEMBL662294

Name: Antibacterial activity was determined against gram positive organism, Streptococcus p...
Source: ChEMBL
Target: Streptococcus pyogenes
External Id: CHEMBL801925

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8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid

3-Quinolinecarboxylicacid,8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo

8-chloro-1-cyclopropyl-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

3-Quinolinecarboxylic acid, 8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-7-(3-Methyl-1-piperazinyl)-4-oxo

Names

Chemical & Physical Properties

Synthetic Route

Bioassay

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.