3-(2,3-dihydro-1,4-benzodioxin-3-ylmethylamino)-N-methylpropanamide

Modify Date: 2024-01-13 22:10:27

3-(2,3-dihydro-1,4-benzodioxin-3-ylmethylamino)-N-methylpropanamide Structure
3-(2,3-dihydro-1,4-benzodioxin-3-ylmethylamino)-N-methylpropanamide structure
Common Name 3-(2,3-dihydro-1,4-benzodioxin-3-ylmethylamino)-N-methylpropanamide
CAS Number 102128-78-9 Molecular Weight 250.29400
Density 1.136g/cm3 Boiling Point 451.7ºC at 760 mmHg
Molecular Formula C13H18N2O3 Melting Point N/A
MSDS N/A Flash Point 227ºC

 Names

Name 3-(2,3-dihydro-1,4-benzodioxin-3-ylmethylamino)-N-methylpropanamide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.136g/cm3
Boiling Point 451.7ºC at 760 mmHg
Molecular Formula C13H18N2O3
Molecular Weight 250.29400
Flash Point 227ºC
Exact Mass 250.13200
PSA 63.08000
LogP 1.78330
Vapour Pressure 2.38E-08mmHg at 25°C
Index of Refraction 1.524

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UE3097200
CHEMICAL NAME :
Propionamide, 3-(((1,4-benzodioxan-2-yl)methyl)amino)-N-methyl-
CAS REGISTRY NUMBER :
102128-78-9
LAST UPDATED :
198910
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C13-H18-N2-O3
MOLECULAR WEIGHT :
250.33
WISWESSER LINE NOTATION :
T66 BO EOT&J C1M2VM1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
350 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 105,317,1956
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 105,317,1956
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
75 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 105,317,1956
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
90 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 105,317,1956 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intramuscular
DOSE :
100 mg/kg
SEX/DURATION :
female 5 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)
REFERENCE :
PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 100,555,1959

 Synonyms

1205 i.s.