4'-demethyl-1-O-ethyl-1-epipodophyllotoxin

Modify Date: 2026-08-21 17:56:04

4'-demethyl-1-O-ethyl-1-epipodophyllotoxin Structure
4'-demethyl-1-O-ethyl-1-epipodophyllotoxin structure
Common Name 4'-demethyl-1-O-ethyl-1-epipodophyllotoxin
CAS Number 102306-95-6 Molecular Weight 428.43200
Density N/A Boiling Point N/A
Molecular Formula C23H24O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name 4'-demethyl-1-O-ethyl-1-epipodophyllotoxin
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C23H24O8
Molecular Weight 428.43200
Exact Mass 428.14700
PSA 92.68000
LogP 3.15040
InChIKey XWWKNDVCCMQSIV-COWZOJLOSA-N
SMILES CCOC1c2cc3c(cc2C(c2cc(OC)c(O)c(OC)c2)C2C(=O)OCC12)OCO3

 Bioassay

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Name: Inhibition of human DNA topoisomerase 2 at 400 uM
Source: ChEMBL
Target: N/A
External Id: CHEMBL962617
Name: Compound was tested for in vitro cytotoxicity in KB cells after 3 days of incubation
Source: ChEMBL
Target: N/A
External Id: CHEMBL885237
Name: Cytotoxicity against human KB cells
Source: ChEMBL
Target: KB
External Id: CHEMBL962618
Name: Compound was tested for inhibition against human DNA topoisomerase II
Source: ChEMBL
Target: DNA topoisomerase 2-beta
External Id: CHEMBL669727
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 Synonyms

4'-demethylepipodophyllotoxin ethyl ether
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