NSC-12
Modify Date: 2024-01-09 12:19:45
NSC-12 structure
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Common Name | NSC-12 | ||
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| CAS Number | 102586-30-1 | Molecular Weight | 484.51500 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H34F6O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of NSC-12NSC 12 is an extracellular trap of fibroblast growth factor 2 (FGF2) that binds FGF2 and interferes with its interaction with FGFR1. NSC12 inhibits the proliferation of different FGF-dependent tumour cells both in vitro and in vivo with no systemic toxic effects[1]. |
| Name | 4,4,4-trifluoro-1-[(8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-3-(trifluoromethyl)butane-1,3-diol |
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| Synonym | More Synonyms |
| Description | NSC 12 is an extracellular trap of fibroblast growth factor 2 (FGF2) that binds FGF2 and interferes with its interaction with FGFR1. NSC12 inhibits the proliferation of different FGF-dependent tumour cells both in vitro and in vivo with no systemic toxic effects[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C24H34F6O3 |
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| Molecular Weight | 484.51500 |
| Exact Mass | 484.24100 |
| PSA | 60.69000 |
| LogP | 5.53300 |
| Storage condition | -20℃ |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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| 21-(Hydroxy(bistrifluoromethyl)methyl)pregnane-3,20-diol |
| Pregn-5-ene-3,20-diol,21-(2-hydroxy-1,1,1,3,3,3-hexafluoro-2-propyl) |
| NSC-12 |