CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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DE8746050
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CHEMICAL NAME :
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5H-2,3-Benzodiazepine, 1-(4-aminophenyl)-7,8-dimethoxy-4-methyl-
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CAS REGISTRY NUMBER :
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102771-12-0
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LAST UPDATED :
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199706
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DATA ITEMS CITED :
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4
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MOLECULAR FORMULA :
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C18-H19-N3-O2
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MOLECULAR WEIGHT :
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309.40
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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128 mg/kg
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TOXIC EFFECTS :
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Lungs, Thorax, or Respiration - other changes Lungs, Thorax, or Respiration - cyanosis Lungs, Thorax, or Respiration - dyspnea
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REFERENCE :
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ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 39,894,1989
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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108 mg/kg
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TOXIC EFFECTS :
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Lungs, Thorax, or Respiration - other changes Lungs, Thorax, or Respiration - cyanosis Lungs, Thorax, or Respiration - dyspnea
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REFERENCE :
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ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 39,894,1989
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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275 mg/kg
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TOXIC EFFECTS :
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Lungs, Thorax, or Respiration - other changes Lungs, Thorax, or Respiration - cyanosis Lungs, Thorax, or Respiration - dyspnea
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REFERENCE :
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ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 39,894,1989
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TYPE OF TEST :
-
LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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182 mg/kg
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TOXIC EFFECTS :
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Lungs, Thorax, or Respiration - other changes Lungs, Thorax, or Respiration - cyanosis Lungs, Thorax, or Respiration - dyspnea
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REFERENCE :
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ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 39,894,1989
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