2,3-DIPHOSPHO-D-GLYCERIC ACID PENTASODIUM SALT

Modify Date: 2024-01-03 20:32:42

2,3-DIPHOSPHO-D-GLYCERIC ACID PENTASODIUM SALT Structure
2,3-DIPHOSPHO-D-GLYCERIC ACID PENTASODIUM SALT structure
Common Name 2,3-DIPHOSPHO-D-GLYCERIC ACID PENTASODIUM SALT
CAS Number 102783-53-9 Molecular Weight 375.946
Density N/A Boiling Point N/A
Molecular Formula C3H3Na5O10P2 Melting Point N/A
MSDS Chinese USA Flash Point N/A

 Use of 2,3-DIPHOSPHO-D-GLYCERIC ACID PENTASODIUM SALT


2,3-Diphospho-D-glyceric acid pentasodium salt is a highly anionic polyphosphorus compound. 2,3-Diphospho-D-glyceric acid is present in the concave center of red blood cells, it binds hemoglobin to reduce its oxygen affinity. 2,3-Diphospho-D-glyceric acid is an endogenous, selective inhibitor of vascular calcification (VC) and significantly delays the formation of crystalline calpain particles (CPP). 2,3-Diphospho-D-glyceric acid also inhibits calcification in mouse vascular smooth muscle cell line (MOVAS) without cytotoxic effects[1].

 Names

Name 2,3-Diphospho-D-glyceric acid pentasodium salt
Synonym More Synonyms

  Biological Activity

Description 2,3-Diphospho-D-glyceric acid pentasodium salt is a highly anionic polyphosphorus compound. 2,3-Diphospho-D-glyceric acid is present in the concave center of red blood cells, it binds hemoglobin to reduce its oxygen affinity. 2,3-Diphospho-D-glyceric acid is an endogenous, selective inhibitor of vascular calcification (VC) and significantly delays the formation of crystalline calpain particles (CPP). 2,3-Diphospho-D-glyceric acid also inhibits calcification in mouse vascular smooth muscle cell line (MOVAS) without cytotoxic effects[1].
Related Catalog
References

[1]. Kharaghani D, Kohno S, Minamizaki T, et al. 2, 3-Diphospho-D-glyceric acid inhibits calciprotein particle growth and calcification in MOVAS cells but not in MC3T3-E1 cells[J]. Colloid and Interface Science Communications, 2022, 50: 100668.

 Chemical & Physical Properties

Molecular Formula C3H3Na5O10P2
Molecular Weight 375.946
Exact Mass 375.868988
PSA 204.59000

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3

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 Synonyms

Pentasodium (2R)-2,3-bis(phosphonatooxy)propanoate
Propanoic acid, 2,3-bis(phosphonooxy)-, sodium salt, (2R)- (1:5)
2,3-diphospho-d-glyceric acid pentasodium salt
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