Propargyl-PEG6-Ms

Modify Date: 2024-01-09 19:25:43

Propargyl-PEG6-Ms Structure
Propargyl-PEG6-Ms structure
Common Name Propargyl-PEG6-Ms
CAS Number 1036204-62-2 Molecular Weight 354.42
Density N/A Boiling Point N/A
Molecular Formula C14H26O8S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Propargyl-PEG6-Ms


Propargyl-PEG5-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Propargyl-PEG5-Ms
Synonym More Synonyms

 Propargyl-PEG6-Ms Biological Activity

Description Propargyl-PEG5-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C14H26O8S
Molecular Weight 354.42

 Synonyms

MFCD20134135