Zolantidine dimaleate
Zolantidine dimaleate structure
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Common Name | Zolantidine dimaleate | ||
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| CAS Number | 104076-39-3 | Molecular Weight | 613.68 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C30H35N3O9S | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
Use of Zolantidine dimaleateZolantidine dimaleate (SKF 95282 dimaleate) is a potent, selective and cross the blood-brain barrier histamine H2 antagonist. Zolantidine dimaleate induces antinociception[1][2]. |
| Name | AL1YII70LM |
|---|---|
| Synonym | More Synonyms |
| Description | Zolantidine dimaleate (SKF 95282 dimaleate) is a potent, selective and cross the blood-brain barrier histamine H2 antagonist. Zolantidine dimaleate induces antinociception[1][2]. |
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| Related Catalog | |
| Target |
H2 Receptor |
| In Vivo | Zolantidine dimaleate (5、10、20、40 mg/kg；皮下注射) 在胆汁淤积大鼠中诱导抗伤害作用[2]。 Animal Model: 200-250 g, male Wistar rats (cholestatic rats)[2] Dosage: 5, 10, 20, 40 mg/kg Administration: S.c. Result: Significantly increased tail-flick latencies and induced antinociception. |
| References |
| Molecular Formula | C30H35N3O9S |
|---|---|
| Molecular Weight | 613.68 |
| Exact Mass | 613.209412 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
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Zolantidine (SK&F 95282) is a potent selective brain-penetrating histamine H2-receptor antagonist.
Br. J. Pharmacol. 93(1) , 69-78, (1988) 1. The novel benzthiazole derivative zolantidine (SK&F 95282) is a potent antagonist of histamine at H2-receptors in guinea-pig atrium and rat uterus. Only apparent pA2 values of 7.46 and 7.26 respect... |
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Linking solubility and permeability assays for maximum throughput and reproducibility.
J. Biomol. Screen. 10(4) , 383-90, (2005) Solubility and permeability are intimately linked in drug absorption processes. They have, however, been traditionally assayed separately. To support this linkage, a combined solubility/permeability a... |
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Identification of novel functional inhibitors of acid sphingomyelinase.
PLoS ONE 6 , e23852, (2011) We describe a hitherto unknown feature for 27 small drug-like molecules, namely functional inhibition of acid sphingomyelinase (ASM). These entities named FIASMAs (Functional Inhibitors of Acid Sphing... |
| 2-Benzothiazolamine, N-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]-, (2Z)-2-butenedioate (1:2) |
| AL1YII70LM |
| Zolantidine dimaleate |
| N-{3-[3-(Piperidin-1-ylmethyl)phenoxy]propyl}-1,3-benzothiazol-2-amine (2Z)-but-2-enedioate (1:2) |
| N-[3-[3-(1-Piperidinylmethyl)phenoxy]propyl]-2-benzothiazolamine dimaleate |
| SKF 95282 dimaleate |
| SKF-95282 dimaleate salt |
| N-{3-[3-(1-Piperidinylmethyl)phenoxy]propyl}-1,3-benzothiazol-2-amine (2Z)-2-butenedioate (1:2) |