Eldecalcitol
Modify Date: 2024-01-02 10:30:02
Eldecalcitol structure
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Common Name | Eldecalcitol | ||
|---|---|---|---|---|
| CAS Number | 104121-92-8 | Molecular Weight | 490.715 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 655.7±55.0 °C at 760 mmHg | |
| Molecular Formula | C30H50O5 | Melting Point | 126-128ºC | |
| MSDS | N/A | Flash Point | 350.3±31.5 °C | |
Use of EldecalcitolEldecalcitol (ED-71; 2.beta.-(3-Hydroxypropoxy)-1.alpha.,25-dihydroxyvitamin D3) is an analog of 1,25-dihydroxyvitamin D3 that improves bone mineral density. IC50 value:Target: Vd analogEldecalcitol (ED-71; 2.beta.-(3-Hydroxypropoxy)-1.alpha.,25-dihydroxyvitamin D3) is more efficacious than alfacalcidol in preventing vertebral and wrist fractures in osteoporotic patients with vitamin D sufficiency, with a safety profile similar to alfacalcidol. |
| Name | (1S,2S,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-2-(3-hydroxypropoxy)-4-methylidenecyclohexane-1,3-diol |
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| Synonym | More Synonyms |
| Description | Eldecalcitol (ED-71; 2.beta.-(3-Hydroxypropoxy)-1.alpha.,25-dihydroxyvitamin D3) is an analog of 1,25-dihydroxyvitamin D3 that improves bone mineral density. IC50 value:Target: Vd analogEldecalcitol (ED-71; 2.beta.-(3-Hydroxypropoxy)-1.alpha.,25-dihydroxyvitamin D3) is more efficacious than alfacalcidol in preventing vertebral and wrist fractures in osteoporotic patients with vitamin D sufficiency, with a safety profile similar to alfacalcidol. |
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| Related Catalog | |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 655.7±55.0 °C at 760 mmHg |
| Melting Point | 126-128ºC |
| Molecular Formula | C30H50O5 |
| Molecular Weight | 490.715 |
| Flash Point | 350.3±31.5 °C |
| Exact Mass | 490.365814 |
| PSA | 90.15000 |
| LogP | 5.84 |
| Vapour Pressure | 0.0±4.5 mmHg at 25°C |
| Index of Refraction | 1.550 |
| Storage condition | 2-8℃ |
| Precursor 8 | |
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| DownStream 0 | |
![(1β,2α,3α,5Z,7E)-1,3-bis[(1,1-dimethylethyl)dimethylsilyloxy]-2-[3-[(1,1-dimethylethyl)dimethylsilyloxy]propoxy]-25-trimethylsilyloxy-9,10-secocholesta-5,7,10(19)-triene Structure](https://image.chemsrc.com/caspic/499/342645-84-5.png)
CAS#:342645-84-5![[3R-(1Z,3β,4α,5α)]-2-[3,5-bis[(1,1-dimethylethyl)dimethylsilyloxy]-4-(3-hydroxypropoxy)-2-methylenecyclohexylidene]ethanol Structure](https://image.chemsrc.com/caspic/252/342644-91-1.png)
CAS#:342644-91-1![(1α,2β,3β,5Z,7E,20S)-1,3-bis[(1,1-dimethylethyl)dimethyl-silyloxy]-2-[3-[(1,1-dimethylethyl)dimethylsilyloxy]propoxy]-9,10-secopregna-5,7,10(19)-triene-20-methyl 4-methylbenzenesulfonate Structure](https://image.chemsrc.com/caspic/051/342645-07-2.png)
CAS#:342645-07-2
CAS#:66774-80-9![[3R-(1Z,3β,4α,5α)]-[2-[3,5-bis[(1,1-dimethylethyl)dimethylsilyloxy]-4-[3-[(1,1-dimethylethyl)dimethylsilyloxy]propoxy]-2-methylenecyclohexylidene]ethyl]diphenylphosphine oxide Structure](https://image.chemsrc.com/caspic/304/200636-54-0.png)
CAS#:200636-54-0![[3R-(1Z,3β,4α,5α)]-2-[5-(1,1-dimethylethyl)dimethylsilyloxy-3,4-isopropylidenedioxy-2-methylenecyclohexylidene]ethanol Structure](https://image.chemsrc.com/caspic/265/244278-87-3.png)
CAS#:244278-87-3![[3R-(1Z,3β,4α,5α)]-2-[3,4,5-trihydroxy-2-methylenecyclohexylidene]ethyl trimethylacetate Structure](https://image.chemsrc.com/caspic/109/377091-68-4.png)
CAS#:377091-68-4![[3R-(1Z,3β,4α,5α)]-2-[5-(1,1-dimethylethyl)dimethylsilyloxy-3,4-isopropylidenedioxy-2-methylenecyclohexylidene]ethyl trimethylacetate Structure](https://image.chemsrc.com/caspic/383/342644-83-1.png)
CAS#:342644-83-1| HY-A0020 |
| ED 71 |
| 9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol, 2-(3-hydroxypropoxy)-, (1α,2β,3β,5Z,7E)- |
| UNII-I2JP8UE90H |
| Eldecalcitol |
| CS-0363 |
| 1,3-Cyclohexanediol, 2-(3-hydroxypropoxy)-4-methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R)-5-hydroxy-1,5-dimethylhexyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-, (1R,2R,3R,5Z)- |
| 1α,25-dihydroxy-2β-(3-hydroxypropoxy)vitamin D3 |
| (1R,2R,3R,5Z,7E)-2-(3-Hydroxypropoxy)-9,10-secocholesta-5,7,10-triene-1,3,25-triol |