Cyclosporin A

Modify Date: 2026-04-02 15:51:25

Cyclosporin A Structure
Cyclosporin A structure
Common Name Cyclosporin A
CAS Number 104250-72-8 Molecular Weight 1202.6
Density N/A Boiling Point N/A
Molecular Formula C62H111N11O12 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name Cyclosporin A

 Chemical & Physical Properties

Molecular Formula C62H111N11O12
Molecular Weight 1202.6
InChIKey PMATZTZNYRCHOR-CGLBZJNRSA-N
SMILES CC[C@H]1C(=O)N(CC(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N1)[C@@H]([C@H](C)C/C=C/C)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C

 Cyclosporin ABioassay

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Name: Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
Source: NCGC
External Id: SNCA-p-activity-luciferase
Name: Inhibition of paw edema formation in mouse after an ip dose of 5 mg/kg; Thickness of ...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL743113
Name: Immunosuppressive activity in human Jurkat cells assessed as reduction in PHA + PMA-i...
Source: ChEMBL
Target: Jurkat
External Id: CHEMBL4311816
Name: Inhibition of paw edema formation in mouse after an ip dose of 50 mg/kg; Thickness of...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL743112
Name: Concentration that reduces difference in reversal of [3H]VBL accumulation between MDA...
Source: ChEMBL
Target: Breast cancer cell line
External Id: CHEMBL879733
Name: Concentration that reduces the difference in reversal of DOX accumulation between MDA...
Source: ChEMBL
Target: Breast cancer cell line
External Id: CHEMBL695434
Name: Ratio of effect of compound on DOX accumulation (antiPgp activity) to its intrinsic c...
Source: ChEMBL
Target: Breast cancer cell line
External Id: CHEMBL695439
Name: Potency relative to progesterone in reducing the difference in reversal of DOX accumu...
Source: ChEMBL
Target: Breast cancer cell line
External Id: CHEMBL694636
Name: Ratio of effect of compound on VBL accumulation (antiPgp activity) to its intrinsic c...
Source: ChEMBL
Target: Breast cancer cell line
External Id: CHEMBL699276
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