DOTMA
Modify Date: 2024-01-09 09:32:20
DOTMA structure
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Common Name | DOTMA | ||
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| CAS Number | 104872-42-6 | Molecular Weight | 670.57500 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C42H84ClNO2 | Melting Point | 35-38℃ | |
| MSDS | N/A | Flash Point | N/A | |
Use of DOTMADOTMA, as a tetra-methylated DOTA analogue, is a cationic lipid and can be used as a non-viral vector for gene therapy. It has been used as a component in liposomes that can be used to encapsulate siRNA, microRNAs, and oligonucleotides and for gene transfection in vitro. It exhibits effective in vitro and in vivo gene transfection. DOTMA induces a positive charge on the liposomes and thus promotes efficient liposome- cell membrane interaction[1][2][3]. |
| Name | N,N,N-trimethyl-2,3-bis(octadec-9-en-1-yloxy)propan-1-aminium chloride |
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| Description | DOTMA, as a tetra-methylated DOTA analogue, is a cationic lipid and can be used as a non-viral vector for gene therapy. It has been used as a component in liposomes that can be used to encapsulate siRNA, microRNAs, and oligonucleotides and for gene transfection in vitro. It exhibits effective in vitro and in vivo gene transfection. DOTMA induces a positive charge on the liposomes and thus promotes efficient liposome- cell membrane interaction[1][2][3]. |
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| Related Catalog | |
| References |
| Melting Point | 35-38℃ |
|---|---|
| Molecular Formula | C42H84ClNO2 |
| Molecular Weight | 670.57500 |
| Exact Mass | 669.61900 |
| PSA | 18.46000 |
| LogP | 13.97140 |
| Storage condition | -20℃ |