2-Amino-6-chloro-9-(3-deoxy-beta-D-ribofuanosyl)-9H-purine

Modify Date: 2023-06-01 10:22:06

2-Amino-6-chloro-9-(3-deoxy-beta-D-ribofuanosyl)-9H-purine Structure
2-Amino-6-chloro-9-(3-deoxy-beta-D-ribofuanosyl)-9H-purine structure
Common Name 2-Amino-6-chloro-9-(3-deoxy-beta-D-ribofuanosyl)-9H-purine
CAS Number 1055035-48-7 Molecular Weight 285.69
Density 2.0±0.1 g/cm3 Boiling Point 681.9±65.0 °C at 760 mmHg
Molecular Formula C10H12ClN5O3 Melting Point N/A
MSDS N/A Flash Point 366.2±34.3 °C

 Use of 2-Amino-6-chloro-9-(3-deoxy-beta-D-ribofuanosyl)-9H-purine


2-Amino-6-chloro-9-(3-deoxy-beta-D-ribofuanosyl)-9H-purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 6-Chloro-9-(3-deoxy-β-D-erythro-pentofuranosyl)-9H-purin-2-amine
Synonym More Synonyms

  Biological Activity

Description 2-Amino-6-chloro-9-(3-deoxy-beta-D-ribofuanosyl)-9H-purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 2.0±0.1 g/cm3
Boiling Point 681.9±65.0 °C at 760 mmHg
Molecular Formula C10H12ClN5O3
Molecular Weight 285.69
Flash Point 366.2±34.3 °C
Exact Mass 285.062866
LogP 0.02
Vapour Pressure 0.0±2.2 mmHg at 25°C
Index of Refraction 1.871

 Synonyms

6-Chloro-9-(3-deoxy-β-D-erythro-pentofuranosyl)-9H-purin-2-amine
9H-Purin-2-amine, 6-chloro-9-(3-deoxy-β-D-erythro-pentofuranosyl)-
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