Cephalexin monohydrochloride
Modify Date: 2024-01-12 09:48:45
Cephalexin monohydrochloride structure
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Common Name | Cephalexin monohydrochloride | ||
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| CAS Number | 105879-42-3 | Molecular Weight | 401.86500 | |
| Density | 1.5g/cm3 | Boiling Point | 727.4ºC at 760mmHg | |
| Molecular Formula | C16H20ClN3O5S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 393.7ºC | |
Use of Cephalexin monohydrochlorideCephalexin (Cefalexin) hydrochloride monohydrate is a potent, orally active new semisynthetic cephalosporin antibiotic with a broad antibacterial spectrum. Cephalexin (Cefalexin) hydrochloride monohydrate has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria. Cephalexin (Cefalexin) hydrochloride monohydrate targets penicillin-binding proteins (PBPs) to inhibit bacterial cell wall assembly. Cephalexin (Cefalexin) hydrochloride monohydrate is used for the research of pneumonia, strep throat, and bacterial endocarditis, et al[1][2]. |
| Name | (6R,7R)-7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,hydrate,hydrochloride |
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| Synonym | More Synonyms |
| Description | Cephalexin (Cefalexin) hydrochloride monohydrate is a potent, orally active new semisynthetic cephalosporin antibiotic with a broad antibacterial spectrum. Cephalexin (Cefalexin) hydrochloride monohydrate has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria. Cephalexin (Cefalexin) hydrochloride monohydrate targets penicillin-binding proteins (PBPs) to inhibit bacterial cell wall assembly. Cephalexin (Cefalexin) hydrochloride monohydrate is used for the research of pneumonia, strep throat, and bacterial endocarditis, et al[1][2]. |
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| Related Catalog | |
| In Vitro | Cephalexin (Cefalexin) hydrochloride monohydrate (10 μg/mL) disrupts polymer peptidoglycan (PG) biogenesis by inactivating enzymes called penicillin-binding proteins (PBPs)[1]. Cephalexin (Cefalexin) hydrochloride monohydrate inhibits a broad spectrum of grampositive and gram-negative organisms with MIC values of 2, 2, 2, 2, 4, 4.4 and 5.7 μg/mL for Bacillus anthracis, Edwardsiella taFda, Vibrio cholera, Pasteurella multocida, Edwardsiella tarda, Alcaligenes sp and Proteus rettgeri, respectively[2]. |
| In Vivo | Cephalexin (Cefalexin) hydrochloride monohydrate (0-50 mg/kg; p.o.; for 3.5 hours) has antibacterial activity in male Swiss-Webster mice with infected bacterial[2]. Animal Model: Male Swiss-Webster mice with infected bacterial[2] Dosage: 0-50 mg/kg Administration: Oral administration; for 3.5 hours Result: Had antibacterial activity against Streptococcus pyogenes, Streptococcus pneumoniae, Staphylococcus aureus and several gram-negative species mice. |
| References |
| Density | 1.5g/cm3 |
|---|---|
| Boiling Point | 727.4ºC at 760mmHg |
| Molecular Formula | C16H20ClN3O5S |
| Molecular Weight | 401.86500 |
| Flash Point | 393.7ºC |
| Exact Mass | 401.08100 |
| PSA | 150.75000 |
| LogP | 2.66110 |
| Vapour Pressure | 3.27E-22mmHg at 25°C |
| Index of Refraction | 1.699 |
| cephalexin hydrochloride monohydrate |
| Cembrandiol |