2-((4-(METHYLTHIO)PHENYL)AMINO)-1-(2-(TRIFLUOROMETHYL)BENZYL)-1H-BENZO[D]IMIDAZOLE-5-CARBOXAMIDE

Modify Date: 2025-08-25 17:50:55

2-((4-(METHYLTHIO)PHENYL)AMINO)-1-(2-(TRIFLUOROMETHYL)BENZYL)-1H-BENZO[D]IMIDAZOLE-5-CARBOXAMIDE Structure
2-((4-(METHYLTHIO)PHENYL)AMINO)-1-(2-(TRIFLUOROMETHYL)BENZYL)-1H-BENZO[D]IMIDAZOLE-5-CARBOXAMIDE structure
Common Name 2-((4-(METHYLTHIO)PHENYL)AMINO)-1-(2-(TRIFLUOROMETHYL)BENZYL)-1H-BENZO[D]IMIDAZOLE-5-CARBOXAMIDE
CAS Number 1092829-83-8 Molecular Weight 456.48300
Density N/A Boiling Point N/A
Molecular Formula C23H19F3N4OS Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name 2-(4-methylsulfanylanilino)-1-[[2-(trifluoromethyl)phenyl]methyl]benzimidazole-5-carboxamide
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C23H19F3N4OS
Molecular Weight 456.48300
Exact Mass 456.12300
PSA 98.24000
LogP 6.44110

 Bioassay

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Name: Selectivity for human HSP over HSET
Source: ChEMBL
Target: N/A
External Id: CHEMBL1035573
Name: Binding Assay from Article 10.1021/bi1005283: "Novel benzimidazole inhibitors bind to...
Source: BindingDB
Target: N/A
External Id: BindingDB_5722_1
Name: Inhibition of Kif3B
Source: ChEMBL
Target: Kinesin-like protein KIF3B
External Id: CHEMBL1035571
Name: Inhibition of nKHC
Source: ChEMBL
Target: Kinesin heavy chain isoform 5A
External Id: CHEMBL1035572
Name: Permeability across human Caco-2 cell membrane
Source: ChEMBL
Target: Caco-2
External Id: CHEMBL1035569
Name: Inhibition of human kinesin spindle protein by endpoint assay
Source: ChEMBL
Target: Kinesin-like protein KIF11
External Id: CHEMBL1035565
Name: Antiproliferative activity against human A2780 cells assessed s occurrence of monostr...
Source: ChEMBL
Target: A2780
External Id: CHEMBL1035578
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 Synonyms

2-((4-(Methylthio)phenyl)amino)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxamide
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