Purine-9-beta-D-(2'-deoxy-2'-fluoro) arabinoriboside

Modify Date: 2024-04-02 23:05:39

Purine-9-beta-D-(2'-deoxy-2'-fluoro) arabinoriboside Structure
Purine-9-beta-D-(2'-deoxy-2'-fluoro) arabinoriboside structure
Common Name Purine-9-beta-D-(2'-deoxy-2'-fluoro) arabinoriboside
CAS Number 109304-16-7 Molecular Weight 254.22
Density 1.9±0.1 g/cm3 Boiling Point 544.8±60.0 °C at 760 mmHg
Molecular Formula C10H11FN4O3 Melting Point N/A
MSDS N/A Flash Point 283.3±32.9 °C

 Use of Purine-9-beta-D-(2'-deoxy-2'-fluoro) arabinoriboside


9-(2’-Deoxy-2’-fluoro-β-D-arabinofuranosyl)-9H-purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name Purine -9-beta-D-(2'-deoxy-2'-fluoro) arabinoriboside
Synonym More Synonyms

  Biological Activity

Description 9-(2’-Deoxy-2’-fluoro-β-D-arabinofuranosyl)-9H-purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.9±0.1 g/cm3
Boiling Point 544.8±60.0 °C at 760 mmHg
Molecular Formula C10H11FN4O3
Molecular Weight 254.22
Flash Point 283.3±32.9 °C
Exact Mass 254.081512
LogP -0.67
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.772

 Synonyms

MFCD25542492
9-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine
9H-Purine, 9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-