Amino-PEG6-acetic acid

Modify Date: 2024-01-10 21:55:35

Amino-PEG6-acetic acid Structure
Amino-PEG6-acetic acid structure
Common Name Amino-PEG6-acetic acid
CAS Number 1104083-46-6 Molecular Weight 339.38
Density N/A Boiling Point N/A
Molecular Formula C14H29NO8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Amino-PEG6-acetic acid


Amino-PEG6-acetic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Amino-PEG6-acetic acid

 Amino-PEG6-acetic acid Biological Activity

Description Amino-PEG6-acetic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

 Chemical & Physical Properties

Molecular Formula C14H29NO8
Molecular Weight 339.38