Acetyl-pepstatin

Modify Date: 2024-04-04 15:25:53

Acetyl-pepstatin Structure
Acetyl-pepstatin structure
Common Name Acetyl-pepstatin
CAS Number 11076-29-2 Molecular Weight 643.812
Density 1.1±0.1 g/cm3 Boiling Point 992.8±65.0 °C at 760 mmHg
Molecular Formula C31H57N5O9 Melting Point N/A
MSDS N/A Flash Point 554.2±34.3 °C

 Use of Acetyl-pepstatin


Acetyl-pepstatin is a high affinity aspartic protease inhibitor. Acetyl-pepstatin inhibits HIV-1 protease (Ki=20 nM at pH 4.7) and HIV-2 protease (Ki= 5 nM at pH 4.7). Antiviral.

 Names

Name acetyl pepstatin
Synonym More Synonyms

 Acetyl-pepstatin Biological Activity

Description Acetyl-pepstatin is a high affinity aspartic protease inhibitor. Acetyl-pepstatin inhibits HIV-1 protease (Ki=20 nM at pH 4.7) and HIV-2 protease (Ki= 5 nM at pH 4.7). Antiviral.
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 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 992.8±65.0 °C at 760 mmHg
Molecular Formula C31H57N5O9
Molecular Weight 643.812
Flash Point 554.2±34.3 °C
Exact Mass 643.415649
PSA 223.26000
LogP 0.75
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.508

 Synonyms

acetyl-pepstatin
N-Acetyl-L-valyl-N-[(3S,4S)-1-{[(2S)-1-{[(2S,3S)-1-carboxy-2-hydroxy-5-methyl-3-hexanyl]amino}-1-oxo-2-propanyl]amino}-3-hydroxy-6-methyl-1-oxo-4-heptanyl]-L-valinamide
pepsatin Ac
L-Valinamide, N-acetyl-L-valyl-N-[(1S,2S)-4-[[(1S)-2-[[(1S)-1-[(1S)-2-carboxy-1-hydroxyethyl]-3-methylbutyl]amino]-1-methyl-2-oxoethyl]amino]-2-hydroxy-1-(2-methylpropyl)-4-oxobutyl]-
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