Valsartan Ethyl Ester

Modify Date: 2024-01-04 16:10:33

Valsartan Ethyl Ester Structure
Valsartan Ethyl Ester structure
Common Name Valsartan Ethyl Ester
CAS Number 1111177-30-0 Molecular Weight 463.572
Density 1.2±0.1 g/cm3 Boiling Point 655.7±65.0 °C at 760 mmHg
Molecular Formula C26H33N5O3 Melting Point N/A
MSDS N/A Flash Point 350.4±34.3 °C

 Use of Valsartan Ethyl Ester


Valsartan Ethyl Ester is an impurity of Valsartan. Valsartan is an angiotensin II receptor antagonist for the treatment of high blood pressure and heart failure[1].

 Names

Name Ethyl N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)-4-biphenylyl]methyl}-L-valinate
Synonym More Synonyms

 Valsartan Ethyl Ester Biological Activity

Description Valsartan Ethyl Ester is an impurity of Valsartan. Valsartan is an angiotensin II receptor antagonist for the treatment of high blood pressure and heart failure[1].
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References

[1]. Shan H, et al. Valsartan ameliorates ageing-induced aorta degeneration via angiotensin II type 1 receptor-mediated ERK activity. J Cell Mol Med. 2014 Jun;18(6):1071-80.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 655.7±65.0 °C at 760 mmHg
Molecular Formula C26H33N5O3
Molecular Weight 463.572
Flash Point 350.4±34.3 °C
Exact Mass 463.258331
LogP 5.83
Vapour Pressure 0.0±2.0 mmHg at 25°C
Index of Refraction 1.562

 Synonyms

L-Valine, N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, ethyl ester
Ethyl N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)-4-biphenylyl]methyl}-L-valinate
(S)-ethyl 2-(N-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)pentanamido)-3-methylbutanoate
Valsartan Ethyl Ester
N-(1-Oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine ethyl ester
Valsartan Impurity 18
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