PF-152
Modify Date: 2025-09-18 12:28:50
PF-152 structure
|
Common Name | PF-152 | ||
|---|---|---|---|---|
| CAS Number | 1112169-64-8 | Molecular Weight | 473.45800 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H24FN7O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PF-152PF-152 is a potent, highly selective and orally bioavailable MMP13 inhibitor with Ki of 1.5 nM, with no activity against MMP3 (Ki>10 uM). |
| Name | N-(4-Fluoro-3-methoxybenzyl)-6-(2-{[(2S,5R)-5-(hydroxymethyl)-1,4 -dioxan-2-yl]methyl}-2H-tetrazol-5-yl)-2-methyl-4-pyrimidinecarbo xamide |
|---|---|
| Synonym | More Synonyms |
| Molecular Formula | C21H24FN7O5 |
|---|---|
| Molecular Weight | 473.45800 |
| Exact Mass | 473.18200 |
| PSA | 146.40000 |
| LogP | 0.68340 |
|
~25%
PF-152 CAS#:1112169-64-8 |
| Literature: PFIZER INC. Patent: WO2009/16498 A1, 2009 ; Location in patent: Page/Page column 152-153 ; WO 2009/016498 A1 |
| Precursor 2 | |
|---|---|
| DownStream 0 | |
| PF-152 |