ENLOPLATIN

Modify Date: 2024-01-12 10:43:39

ENLOPLATIN Structure
ENLOPLATIN structure
Common Name ENLOPLATIN
CAS Number 111523-41-2 Molecular Weight 481.40200
Density N/A Boiling Point 241ºC at 760 mmHg
Molecular Formula C13H22N2O5Pt Melting Point N/A
MSDS N/A Flash Point 105.5ºC

 Names

Name [4-(aminomethyl)oxan-4-yl]methanamine,cyclobutane-1,1-dicarboxylate,platinum(2+)
Synonym More Synonyms

 Chemical & Physical Properties

Boiling Point 241ºC at 760 mmHg
Molecular Formula C13H22N2O5Pt
Molecular Weight 481.40200
Flash Point 105.5ºC
Exact Mass 481.11800
PSA 113.87000
LogP 1.27040
Vapour Pressure 0.0368mmHg at 25°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TP2275818
CHEMICAL NAME :
Platinum, (1,1-cyclobutanedicarboxylato(2-))(tetrahydro-4H-pyra n-4,4-dimethanamine-N ,N')-, (SP-4-2)-
CAS REGISTRY NUMBER :
111523-41-2
LAST UPDATED :
199406
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C13-H22-N2-O5-Pt
MOLECULAR WEIGHT :
481.46

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 17,459,1992
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
75 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 17,459,1992

 Synonyms

Enloplatin (USAN/INN)
cis-{Pt(THPDMA)(CBDC)}
{1,1-cyclobutanedicarboxylato(2-)-O,O'}{tetrahydro-4H-pyran-4,4-dimethanamine}platinum(II)
Platinum,[1,1-cyclobutanedi(carboxylato-kO)(2-)](tetrahydro-4H-pyran-4,4-dimethanamine-kN4,kN4')-,(SP-4-2)-(9CI)