Fura 2 pentapotassium salt

Modify Date: 2024-01-09 21:54:55

Fura 2 pentapotassium salt Structure
Fura 2 pentapotassium salt structure
Common Name Fura 2 pentapotassium salt
CAS Number 113694-64-7 Molecular Weight 831.98800
Density N/A Boiling Point 983.5ºC at 760 mmHg
Molecular Formula C29H22K5N3O14 Melting Point N/A
MSDS Chinese USA Flash Point 548.6ºC

 Use of Fura 2 pentapotassium salt


Fura-2 pentapotassium is a scaled fluorescent dye that can be used for intracellular calcium imaging with the Kd value of 140 nM. Fura-2 pentapotassium has an emission wavelength of 510 nm and excitation wavelengths of 340 nm or 380 nm and the ratio of 340/380 fluorescence intensity is proportional to the intracellular Ca2+ level[1][2].

 Names

Name Fura 2 pentapotassium salt
Synonym More Synonyms

 Fura 2 pentapotassium salt Biological Activity

Description Fura-2 pentapotassium is a scaled fluorescent dye that can be used for intracellular calcium imaging with the Kd value of 140 nM. Fura-2 pentapotassium has an emission wavelength of 510 nm and excitation wavelengths of 340 nm or 380 nm and the ratio of 340/380 fluorescence intensity is proportional to the intracellular Ca2+ level[1][2].
Related Catalog
In Vitro Fura-2 pentapotassium (10 μM, 2 min) can be used to detect changes in the concentration of calcium ions in neutrophils of heparinized peripheral blood[1]. Fura-2 pentapotassium (10 μM, 5 min) can be used as a calcium probe to assess the distribution of calcium ions within heart mitochondria without affecting the activity of it in rat[2].
References

[1]. Omar Rafael Alemán, et al. The Antibody Receptor Fc Gamma Receptor IIIb Induces Calcium Entry via Transient Receptor Potential Melastatin 2 in Human Neutrophils. Front Immunol. 2021 May 13;12:657393. doi: 10.3389/fimmu.2021.657393.

[2]. James G. McCormack, et al. Studies on mitochondrial Ca2+-transport and matrix Ca2+ using fura-2-loaded rat heart mitochondria. Biochim Biophys Acta. 1989 Mar 23;973(3):420-7.

 Chemical & Physical Properties

Boiling Point 983.5ºC at 760 mmHg
Molecular Formula C29H22K5N3O14
Molecular Weight 831.98800
Flash Point 548.6ºC
Exact Mass 830.92900
PSA 264.76000
Vapour Pressure 0mmHg at 25°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport

 Synonyms

FURA 2 PENTAPOTASSIUM SALT
Fura-2,pentapotassium salt
MFCD00083328