(Z)-FeCP-oxindole

Modify Date: 2024-01-09 22:52:22

(Z)-FeCP-oxindole structure	Common Name	(Z)-FeCP-oxindole
	CAS Number	1137967-28-2	Molecular Weight	329.173
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₉H₁₅FeNO	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of (Z)-FeCP-oxindole

(Z)-FeCP-oxindole is a selective human vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with an IC50 value of 200 nM. (Z)-FeCP-oxindole can significantly inhibit VEGFR1 and PDGFRa or b at 10 μM. (Z)-FeCP-oxindole has some anticancer activity, acting on B16 murine melanoma lines with IC50 less than 1 μM[1].

Name	(Z)-FeCP-oxindole
Synonym	More Synonyms

Description	(Z)-FeCP-oxindole is a selective human vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with an IC50 value of 200 nM. (Z)-FeCP-oxindole can significantly inhibit VEGFR1 and PDGFRa or b at 10 μM. (Z)-FeCP-oxindole has some anticancer activity, acting on B16 murine melanoma lines with IC50 less than 1 μM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> VEGFR
References	[1]. John Spencer, et al. Synthesis and evaluation of metallocene containing methylidene-1,3-dihydro-2H-indol-2-ones as kinase inhibitors. Metallomics. 2011 Jun;3(6):600-8.

Molecular Formula	C₁₉H₁₅FeNO
Molecular Weight	329.173
Exact Mass	329.050293

Iron(2+) 2,4-cyclopentadienide 2-[(Z)-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-cyclopentadienide (1:1:1)

(Z)-FeCP-oxindole

Use of (Z)-FeCP-oxindole

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(Z)-FeCP-oxindole Biological Activity

Chemical & Physical Properties

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