2-[4-(3-Methyl-2-pyrazinyl)phenyl]-N-{(1R)-1-[5-(2,2,2-trifluoroe thoxy)-2-pyridinyl]ethyl}acetamide
Modify Date: 2025-09-11 17:02:50
![2-[4-(3-Methyl-2-pyrazinyl)phenyl]-N-{(1R)-1-[5-(2,2,2-trifluoroe thoxy)-2-pyridinyl]ethyl}acetamide Structure](https://image.chemsrc.com/caspic/454/1146395-46-1.png)
2-[4-(3-Methyl-2-pyrazinyl)phenyl]-N-{(1R)-1-[5-(2,2,2-trifluoroe thoxy)-2-pyridinyl]ethyl}acetamide structure
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Common Name | 2-[4-(3-Methyl-2-pyrazinyl)phenyl]-N-{(1R)-1-[5-(2,2,2-trifluoroe thoxy)-2-pyridinyl]ethyl}acetamide | ||
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| CAS Number | 1146395-46-1 | Molecular Weight | 430.42300 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H21F3N4O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
| Name | 2-[4-(3-Methyl-2-pyrazinyl)phenyl]-N-{(1R)-1-[5-(2,2,2-trifluoroe thoxy)-2-pyridinyl]ethyl}acetamide |
|---|
| Molecular Formula | C22H21F3N4O2 |
|---|---|
| Molecular Weight | 430.42300 |
| Exact Mass | 430.16200 |
| PSA | 80.49000 |
| LogP | 5.04830 |
| InChIKey | OURCOVUGQRXRTE-CQSZACIVSA-N |
| SMILES | Cc1nccnc1-c1ccc(CC(=O)NC(C)c2ccc(OCC(F)(F)F)cn2)cc1 |
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~75%
2-[4-(3-Methyl-... CAS#:1146395-46-1 |
| Literature: MERCK and CO., INC. Patent: WO2009/54984 A1, 2009 ; Location in patent: Page/Page column 43-44 ; |
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~%
2-[4-(3-Methyl-... CAS#:1146395-46-1 |
| Literature: Yang, Zhi-Qiang; Schlegel, Kelly-Ann S.; Shu, Youheng; Reger, Thomas S.; Cube, Rowena; Mattern, Christa; Coleman, Paul J.; Small, Jim; Hartman, George D.; Ballard, Jeanine; Tang, Cuyue; Kuo, Yuhsin; Prueksaritanont, Thomayant; Nuss, Cindy E.; Doran, Scott; Fox, Steve V.; Garson, Susan L.; Li, Yuxing; Kraus, Richard L.; Uebele, Victor N.; Taylor, Adekemi B.; Zeng, Wei; Fang, Wei; Chavez-Eng, Cynthia; Troyer, Matthew D.; Luk, Julie Ann; Laethem, Tine; Cook, William O.; Renger, John J.; Barrow, James C. ACS Medicinal Chemistry Letters, 2010 , vol. 1, # 9 p. 504 - 509 |
![2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-N-{(1R)-1-[5-(2,2,2-trifluoroethoxy)pyridin-2-yl]ethyl}acetamide structure](https://image.chemsrc.com/caspic/078/1146395-43-8.png)
![(1R)-1-[5-(2,2,2-trifluoroethoxy)-2-pyridyl]ethanamine structure](https://image.chemsrc.com/caspic/353/953780-33-1.png)
![[4-(3-Methyl-2-pyrazinyl)phenyl]acetic acid structure](https://image.chemsrc.com/caspic/346/1240606-62-5.png)
| Precursor 3 | |
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| DownStream 0 | |