2-[4-(3-Methyl-2-pyrazinyl)phenyl]-N-{(1R)-1-[5-(2,2,2-trifluoroe thoxy)-2-pyridinyl]ethyl}acetamide

Modify Date: 2025-09-11 17:02:50

2-[4-(3-Methyl-2-pyrazinyl)phenyl]-N-{(1R)-1-[5-(2,2,2-trifluoroe thoxy)-2-pyridinyl]ethyl}acetamide structure	Common Name	2-[4-(3-Methyl-2-pyrazinyl)phenyl]-N-{(1R)-1-[5-(2,2,2-trifluoroe thoxy)-2-pyridinyl]ethyl}acetamide
	CAS Number	1146395-46-1	Molecular Weight	430.42300
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₂₁F₃N₄O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Name	2-[4-(3-Methyl-2-pyrazinyl)phenyl]-N-{(1R)-1-[5-(2,2,2-trifluoroe thoxy)-2-pyridinyl]ethyl}acetamide

Molecular Formula	C₂₂H₂₁F₃N₄O₂
Molecular Weight	430.42300
Exact Mass	430.16200
PSA	80.49000
LogP	5.04830

2-Chlor-3-methylpyrazin structure

2-Chlor-3-methy...

CAS#:95-58-9

2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-N-{(1R)-1-[5-(2,2,2-trifluoroethoxy)pyridin-2-yl]ethyl}acetamide structure

2-[4-(4,4,5,5-t...

CAS#:1146395-43-8

~75%

2-[4-(3-Methyl-2-pyrazinyl)phenyl]-N-{(1R)-1-[5-(2,2,2-trifluoroe thoxy)-2-pyridinyl]ethyl}acetamide Structure

2-[4-(3-Methyl-...

CAS#:1146395-46-1

Literature: MERCK and CO., INC. Patent: WO2009/54984 A1, 2009 ; Location in patent: Page/Page column 43-44 ;

(1R)-1-[5-(2,2,2-trifluoroethoxy)-2-pyridyl]ethanamine structure

(1R)-1-[5-(2,2,...

CAS#:953780-33-1

[4-(3-Methyl-2-pyrazinyl)phenyl]acetic acid structure

[4-(3-Methyl-2-...

CAS#:1240606-62-5

~%

2-[4-(3-Methyl-2-pyrazinyl)phenyl]-N-{(1R)-1-[5-(2,2,2-trifluoroe thoxy)-2-pyridinyl]ethyl}acetamide Structure

2-[4-(3-Methyl-...

CAS#:1146395-46-1

Literature: Yang, Zhi-Qiang; Schlegel, Kelly-Ann S.; Shu, Youheng; Reger, Thomas S.; Cube, Rowena; Mattern, Christa; Coleman, Paul J.; Small, Jim; Hartman, George D.; Ballard, Jeanine; Tang, Cuyue; Kuo, Yuhsin; Prueksaritanont, Thomayant; Nuss, Cindy E.; Doran, Scott; Fox, Steve V.; Garson, Susan L.; Li, Yuxing; Kraus, Richard L.; Uebele, Victor N.; Taylor, Adekemi B.; Zeng, Wei; Fang, Wei; Chavez-Eng, Cynthia; Troyer, Matthew D.; Luk, Julie Ann; Laethem, Tine; Cook, William O.; Renger, John J.; Barrow, James C. ACS Medicinal Chemistry Letters, 2010 , vol. 1, # 9 p. 504 - 509

Precursor 3
CAS#:95-58-9 2-Chlor-3-methy... CAS#:1146395-43-8 2-[4-(4,4,5,5-t... CAS#:953780-33-1 (1R)-1-[5-(2,2,...
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