2'-Deoxy-2'-fluoro-5-trifluoromethyl-arabinouridine

Modify Date: 2024-01-08 18:53:18

2'-Deoxy-2'-fluoro-5-trifluoromethyl-arabinouridine Structure
2'-Deoxy-2'-fluoro-5-trifluoromethyl-arabinouridine structure
Common Name 2'-Deoxy-2'-fluoro-5-trifluoromethyl-arabinouridine
CAS Number 114652-80-1 Molecular Weight 314.19
Density 1.7±0.1 g/cm3 Boiling Point N/A
Molecular Formula C10H10F4N2O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2'-Deoxy-2'-fluoro-5-trifluoromethyl-arabinouridine


2′-Deoxy-2′-fluoro-5-triflu oromethyl-arabinouridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1].

 Names

Name 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-(trifluoromethyl)-2,4(1H,3H)-pyrimidinedione
Synonym More Synonyms

  Biological Activity

Description 2′-Deoxy-2′-fluoro-5-triflu oromethyl-arabinouridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1].
Related Catalog
References

[1]. Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16(9):7980-93.  

 Chemical & Physical Properties

Density 1.7±0.1 g/cm3
Molecular Formula C10H10F4N2O5
Molecular Weight 314.19
Exact Mass 314.052582
LogP 0.46
Index of Refraction 1.536

 Synonyms

1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-(trifluoromethyl)-2,4(1H,3H)-pyrimidinedione
2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-(trifluoromethyl)-
MFCD00877795