N-Succinimidyl 4-(2-pyridyldithio)butanoate
Modify Date: 2024-01-04 17:55:12
N-Succinimidyl 4-(2-pyridyldithio)butanoate structure
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Common Name | N-Succinimidyl 4-(2-pyridyldithio)butanoate | ||
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| CAS Number | 115088-06-7 | Molecular Weight | 326.391 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 480.1±55.0 °C at 760 mmHg | |
| Molecular Formula | C13H14N2O4S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 244.2±31.5 °C | |
Use of N-Succinimidyl 4-(2-pyridyldithio)butanoateSPDB is a small fragment that can linked DM4 conjugates. Conjugated to antibodies utilizing disulfide linkers: anti-EGFR-SPDB-DM4 has been widely used. |
| Name | 1-{[4-(2-Pyridinyldisulfanyl)butanoyl]oxy}-2,5-pyrrolidinedione |
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| Synonym | More Synonyms |
| Description | SPDB is a small fragment that can linked DM4 conjugates. Conjugated to antibodies utilizing disulfide linkers: anti-EGFR-SPDB-DM4 has been widely used. |
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| Related Catalog | |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 480.1±55.0 °C at 760 mmHg |
| Molecular Formula | C13H14N2O4S2 |
| Molecular Weight | 326.391 |
| Flash Point | 244.2±31.5 °C |
| Exact Mass | 326.039490 |
| LogP | 1.21 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.637 |
| Storage condition | 2-8℃ |
| 1-{[4-(2-Pyridinyldisulfanyl)butanoyl]oxy}-2,5-pyrrolidinedione |
| 2,5-Pyrrolidinedione, 1-[1-oxo-4-(2-pyridinyldithio)butoxy]- |
| SPDB |