(+)-PHENSERINE

Modify Date: 2024-01-10 15:57:06

(+)-PHENSERINE structure	Common Name	(+)-PHENSERINE
	CAS Number	116839-68-0	Molecular Weight	337.41600
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₂₃N₃O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of (+)-PHENSERINE

(+)-Phenserine is a novel selective cholinesterase noncompetitive inhibitor with an IC50 of 45.3 μM.

Name	(3aR,8aS)-1,3a,8-Trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]i ndol-5-yl phenylcarbamate
Synonym	More Synonyms

Description	(+)-Phenserine is a novel selective cholinesterase noncompetitive inhibitor with an IC50 of 45.3 μM.
Related Catalog	Signaling Pathways >> Neuronal Signaling >> AChE Research Areas >> Neurological Disease Research Areas >> Endocrinology
Target	IC50: 45.3 μM (AChE), Ki: 48 μM (AChE).
References	[1]. al-Jafari AA, et al. Kinetics of human erythrocyte acetylcholinesterase inhibition by a novel derivative of physostigmine: phenserine. Biochem Biophys Res Commun. 1998 Jul 9; 248(1):180-5.

Molecular Formula	C₂₀H₂₃N₃O₂
Molecular Weight	337.41600
Exact Mass	337.17900
PSA	48.30000
LogP	3.68310

(+)-PHENSERINE