BMS-665053
Modify Date: 2024-01-05 19:43:07
BMS-665053 structure
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Common Name | BMS-665053 | ||
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| CAS Number | 1173435-64-7 | Molecular Weight | 424.65700 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C16H14Cl3F2N3O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BMS-665053BMS-665053 is a corticotropin-releasing factor-1 (CRF1) receptor antagonist (IC50 = 1.0 nM). BMS-665053)11 is a potent inhibitor of CRF-stimulated cyclic adenosine monophosphate (cAMP) production in human Y-79 retinoblastoma cells (IC50 = 4.9 nM)[1]. |
| Name | 5-Chloro-1-[(1S)-1-cyclopropylethyl]-3-{[2,6-dichloro-4-(difluoro methoxy)phenyl]amino}-2(1H)-pyrazinone |
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| Synonym | More Synonyms |
| Description | BMS-665053 is a corticotropin-releasing factor-1 (CRF1) receptor antagonist (IC50 = 1.0 nM). BMS-665053)11 is a potent inhibitor of CRF-stimulated cyclic adenosine monophosphate (cAMP) production in human Y-79 retinoblastoma cells (IC50 = 4.9 nM)[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C16H14Cl3F2N3O2 |
|---|---|
| Molecular Weight | 424.65700 |
| Exact Mass | 423.01200 |
| PSA | 59.38000 |
| LogP | 4.94140 |
![2-[[(1S)-1-cyclopropylethyl]amino]acetonitrile;hydrochloride structure](https://image.chemsrc.com/caspic/496/1173434-71-3.png)
| 1-Boc-D-Pyroglutamic acid ethyl ester |
| Ethyl Boc-D-pyroglutamate |
| Ethyl N-Boc-D-pyroglutamate |