13-​cis Acitretin D3

Modify Date: 2024-09-16 07:48:12

13-​cis Acitretin D3 Structure
13-​cis Acitretin D3 structure
Common Name 13-​cis Acitretin D3
CAS Number 1185241-03-5 Molecular Weight 326.42934
Density N/A Boiling Point N/A
Molecular Formula C21H23D3O3 Melting Point 178-180°C
MSDS N/A Flash Point N/A

 Use of 13-​cis Acitretin D3


13-cis Acitretin D3 (Isoacitretin D3) is a deuterium labeled 13-cis Acitretin. 13-cis Acitretin is the metabolite of Acitretin after chronic administration. Acitretin(Ro 10-1670) is a second-generation, systemic retinoid that has been used in the treatment of psoriasis[1][2].

 Names

Name 13-CIS-ACITRETIN-D3

 13-​cis Acitretin D3 Biological Activity

Description 13-cis Acitretin D3 (Isoacitretin D3) is a deuterium labeled 13-cis Acitretin. 13-cis Acitretin is the metabolite of Acitretin after chronic administration. Acitretin(Ro 10-1670) is a second-generation, systemic retinoid that has been used in the treatment of psoriasis[1][2].
Related Catalog
References

[1]. A E Stuck, et al. Pharmacokinetics of acitretin and its 13-cis metabolite in patients on haemodialysis. Br J Clin Pharmacol. 1989 Mar; 27(3): 301–304.

[2]. Berbis P, et al. Residual plasma concentrations of acitretin (Ro 10-1670) and its metabolite (Ro 13-7652) after chronic administration. Dermatologica. 1988;177(4):244-6.

 Chemical & Physical Properties

Melting Point 178-180°C
Molecular Formula C21H23D3O3
Molecular Weight 326.42934
Storage condition Amber Vial, -86°C Freezer, Under Inert Atmosphere