N'-(5-Bromo-2-hydroxybenzylidene)-4-methylbenzenesulfonohydrazide
Modify Date: 2024-01-08 19:45:23
N'-(5-Bromo-2-hydroxybenzylidene)-4-methylbenzenesulfonohydrazide structure
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Common Name | N'-(5-Bromo-2-hydroxybenzylidene)-4-methylbenzenesulfonohydrazide | ||
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| CAS Number | 118719-16-7 | Molecular Weight | 369.23 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 509.6±60.0 °C at 760 mmHg | |
| Molecular Formula | C14H13BrN2O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 262.0±32.9 °C | |
Use of N'-(5-Bromo-2-hydroxybenzylidene)-4-methylbenzenesulfonohydrazidedCeMM1 is a RBM39 glue degrader. dCeMM1 shows functions by re-directing the activity of the CRL4DCAF15 ligase. dCeMM1 decreases the expression of RBM39 levels in WT KBM7 cells[1]. |
| Name | MFCD00415337 |
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| Synonym | More Synonyms |
| Description | dCeMM1 is a RBM39 glue degrader. dCeMM1 shows functions by re-directing the activity of the CRL4DCAF15 ligase. dCeMM1 decreases the expression of RBM39 levels in WT KBM7 cells[1]. |
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| Related Catalog | |
| In Vitro | dCeMM1 (0-100 µM; 3 days) 抑制细胞生长，WT 和 UBE2Mmut KBM7 细胞的 EC50 分别为 3、8 µM[1 ]. dCeMM1 (10 µM; 12, 16 h) 降低 WT KBM7 细胞中 RBM39 的表达水平[1]。 Western Blot Analysis[1] Cell Line: WT and UBE2Mmut KBM7 cells Concentration: 10 µM Incubation Time: 12, 16 h Result: Decreased the expression of RBM39 levels in WT KBM7 cells. |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 509.6±60.0 °C at 760 mmHg |
| Molecular Formula | C14H13BrN2O3S |
| Molecular Weight | 369.23 |
| Flash Point | 262.0±32.9 °C |
| Exact Mass | 367.983032 |
| LogP | 4.53 |
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
| Index of Refraction | 1.637 |
| Storage condition | 2-8°C |
| EINECS 657-003-0 |