SOR-C13

Modify Date: 2025-09-11 20:34:23

SOR-C13 Structure
SOR-C13 structure
 Common Name SOR-C13
CAS Number 1187852-48-7 Molecular Weight 1565.81
Density N/A Boiling Point N/A
Molecular Formula C72H116N20O19 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SOR-C13


SOR-C13, a carboxy-terminal truncated peptide, is a high-affinity TRPV6 antagonist with an IC50 value of 14 nM. TRPV6 is a non-voltage gated calcium channel that is associated with malignancy and poor prognosis in breast cancer. SOR-C13 has anticancer activity[1].

 Names

Name SOR-C13

 SOR-C13 Biological Activity

Description SOR-C13, a carboxy-terminal truncated peptide, is a high-affinity TRPV6 antagonist with an IC50 value of 14 nM. TRPV6 is a non-voltage gated calcium channel that is associated with malignancy and poor prognosis in breast cancer. SOR-C13 has anticancer activity[1].
Related Catalog
In Vivo SOR-C13 (i.p.; 400,600 or 800 mg/kg; daily; on days 1 to 12) can effectively inhibit the growth of tumor in female NOD/SCID mice with SKOV-3 cell[2].
References

[1]. S Fu , et al. Erratum to: First-in-human phase I study of SOR-C13, a TRPV6 calcium channel inhibitor, in patients with advanced solid tumors. Invest New Drugs. 2017 Jun;35(3):397. 

[2]. Hui Xue, et al. Inhibition of Transient Receptor Potential Vanilloid 6 channel, elevated in human ovarian cancers, reduces tumour growth in a xenograft model. J Cancer. 2018 Aug 6;9(17):3196-3207. 

 Chemical & Physical Properties

Molecular Formula C72H116N20O19
Molecular Weight 1565.81
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here

Get all suppliers and price by the below link:

SOR-C13 suppliers

SOR-C13 price

Related Compounds: More...
Hydrocarbons, C13-C23, n-alkanes, isoalkanes, cyclics, < 0.03% aromatics
1335203-18-3
Amides, C13-17, N-methyl-N-[2-[methyl[2-(methylamino)ethyl]amino]ethyl], tris(Me sulfates)
85681-78-3
Sulfonamides, C13-17-branched alkane
91082-00-7
Amines, C13-15-alkyldimethyl
70955-13-4
Alcohols, C13-15-branched and linear, butoxylated ethoxylated
111905-53-4
Betaines, (C13-15-branched and linear alkyl)dimethyl
95465-84-2
Epoxides, C13-16-alkyl
66587-57-3
Alkanes, C13-17
90622-45-0
ALKYLETHOXYLATESULPHATE(C13-C15)
27731-62-0
5-bromo-N-{2-[2-(3,4-dimethoxyphenyl)-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-yl]ethyl}furan-2-carboxamide
894043-21-1
2-(2-{[(4-chlorophenyl)carbamoyl]amino}-1,3-thiazol-4-yl)-N-(4-methyl-1,3-benzothiazol-2-yl)acetamide
897620-94-9
N-(2-(1H-indol-3-yl)ethyl)-2-(2-(3-(4-chlorophenyl)ureido)thiazol-4-yl)acetamide
897620-99-4
Methyl 4-[2-(2-{[(3-chlorophenyl)carbamoyl]amino}-1,3-thiazol-4-yl)acetamido]benzoate
897621-32-8
2-(2-{[(3-chlorophenyl)carbamoyl]amino}-1,3-thiazol-4-yl)-N-(3-fluoro-4-methylphenyl)acetamide
897621-44-2
N-(4-butylphenyl)-2-(2-(3-(2-methoxyphenyl)ureido)thiazol-4-yl)acetamide
897622-08-1
2-(2-{[(2-methoxyphenyl)carbamoyl]amino}-1,3-thiazol-4-yl)-N-[4-(trifluoromethyl)phenyl]acetamide
897613-89-7
2-(2-(3-(2-methoxyphenyl)ureido)thiazol-4-yl)-N-(4-(trifluoromethoxy)phenyl)acetamide
897613-92-2
N-[4-(dimethylamino)phenyl]-2-(2-{[(2-methoxyphenyl)carbamoyl]amino}-1,3-thiazol-4-yl)acetamide
897613-93-3
Methyl 4-(2-(2-(3-(2-methoxyphenyl)ureido)thiazol-4-yl)acetamido)benzoate
897613-94-4
Chemsrc provides SOR-C13(CAS#:1187852-48-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of SOR-C13 are included as well.>> amp version: SOR-C13

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved