2-(2-Phenylacetamido)acetic acid-d5

Modify Date: 2024-01-06 21:13:12

2-(2-Phenylacetamido)acetic acid-d5 Structure
2-(2-Phenylacetamido)acetic acid-d5 structure
Common Name 2-(2-Phenylacetamido)acetic acid-d5
CAS Number 1189920-31-7 Molecular Weight 198.23
Density 1.2±0.1 g/cm3 Boiling Point 476.5±38.0 °C at 760 mmHg
Molecular Formula C10H6D5NO3 Melting Point N/A
MSDS N/A Flash Point 242.0±26.8 °C

 Use of 2-(2-Phenylacetamido)acetic acid-d5


2-(2-Phenylacetamido)acetic acid-d5 is the deuterium labeled 2-(2-Phenylacetamido)acetic acid. 2-(2-Phenylacetamido)acetic acid is an endogenous metabolite.

 Names

Name N-[(2H5)Phenylacetyl]glycine
Synonym More Synonyms

 2-(2-Phenylacetamido)acetic acid-d5 Biological Activity

Description 2-(2-Phenylacetamido)acetic acid-d5 is the deuterium labeled 2-(2-Phenylacetamido)acetic acid. 2-(2-Phenylacetamido)acetic acid is an endogenous metabolite.
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 476.5±38.0 °C at 760 mmHg
Molecular Formula C10H6D5NO3
Molecular Weight 198.23
Flash Point 242.0±26.8 °C
Exact Mass 198.105270
LogP 0.18
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.558

 Synonyms

Glycine, N-[2-(phenyl-d5)acetyl]-
N-[(2H5)Phenylacetyl]glycine