N-{3-[5-(2-chloro-4-pyrimidinyl)-2-(1,1-diethylethyl)-1,3-thiazol-4-yl]-2-fluoraphenyl}-2,6-difluorobenzenesulfonamide structure
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Common Name | N-{3-[5-(2-chloro-4-pyrimidinyl)-2-(1,1-diethylethyl)-1,3-thiazol-4-yl]-2-fluoraphenyl}-2,6-difluorobenzenesulfonamide | ||
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CAS Number | 1195768-23-0 | Molecular Weight | 538.993 | |
Density | 1.5±0.1 g/cm3 | Boiling Point | 635.5±65.0 °C at 760 mmHg | |
Molecular Formula | C23H18ClF3N4O2S2 | Melting Point | N/A | |
MSDS | N/A | Flash Point | 338.1±34.3 °C |
Name | N-{3-[5-(2-chloro-4-pyrimidinyl)-2-(1,1-dimethylethyl)-1,3-thiazol-4-yl]-2-fluorophenyl}-2,6-difluorobenzenesulfonamide |
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Synonym | More Synonyms |
Density | 1.5±0.1 g/cm3 |
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Boiling Point | 635.5±65.0 °C at 760 mmHg |
Molecular Formula | C23H18ClF3N4O2S2 |
Molecular Weight | 538.993 |
Flash Point | 338.1±34.3 °C |
Exact Mass | 538.051208 |
PSA | 121.46000 |
LogP | 4.12 |
Vapour Pressure | 0.0±1.9 mmHg at 25°C |
Index of Refraction | 1.613 |
~% N-{3-[5-(2-chlo... CAS#:1195768-23-0 |
Literature: GLAXOSMITHKLINE LLC; DUMBLE, Melissa; KUMAR, Rakesh; LAQUERRE, Sylvie; LEBOWITZ, Peter Patent: WO2011/47238 A1, 2011 ; |
~% N-{3-[5-(2-chlo... CAS#:1195768-23-0 |
Literature: Rheault, Tara R.; Stellwagen, John C.; Adjabeng, George M.; Hornberger, Keith R.; Petrov, Kimberly G.; Waterson, Alex G.; Dickerson, Scott H.; Mook, Robert A.; Laquerre, Sylvie G.; King, Alastair J.; Rossanese, Olivia W.; Arnone, Marc R.; Smitheman, Kimberly N.; Kane-Carson, Laurie S.; Han, Chao; Moorthy, Ganesh S.; Moss, Katherine G.; Uehling, David E. ACS Medicinal Chemistry Letters, 2013 , vol. 4, # 3 p. 358 - 362 |
N-{3-[5-(2-chloro-4-pyrimidinyl)-2-(1,1-diethylethyl)-1,3-thiazol-4-yl]-2-fluoraphenyl}-2,6-difluorobenzenesulfonamide |
Benzenesulfonamide, N-[3-[5-(2-chloro-4-pyrimidinyl)-2-(1,1-dimethylethyl)-4-thiazolyl]-2-fluorophenyl]-2,6-difluoro- |
N-{3-[5-(2-Chloro-4-pyrimidinyl)-2-(2-methyl-2-propanyl)-1,3-thiazol-4-yl]-2-fluorophenyl}-2,6-difluorobenzenesulfonamide |