5-Chloro-2',3'-dideoxy-3'-fluoro-uridine

Modify Date: 2024-01-12 10:21:34

5-Chloro-2',3'-dideoxy-3'-fluoro-uridine Structure
5-Chloro-2',3'-dideoxy-3'-fluoro-uridine structure
 Common Name 5-Chloro-2',3'-dideoxy-3'-fluoro-uridine
CAS Number 119644-22-3 Molecular Weight 264.64
Density 1.6±0.1 g/cm3 Boiling Point N/A
Molecular Formula C9H10ClFN2O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 5-Chloro-2',3'-dideoxy-3'-fluoro-uridine


Raluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 5-chloro-1-[(2R,4S,5R)-4-fluoro-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
Synonym More Synonyms

 5-Chloro-2',3'-dideoxy-3'-fluoro-uridine Biological Activity

Description Raluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Molecular Formula C9H10ClFN2O4
Molecular Weight 264.64
Exact Mass 264.031311
PSA 84.32000
LogP -0.75
Index of Refraction 1.588

 Synonyms

Raluridine
Fddclurd
FddClU
Uridine, 5-chloro-2',3'-dideoxy-3'-fluoro-
935U83
FddCIU
5-Chloro-2',3'-dideoxy-3'-fluorouridine
BW 935U83
2',3'-Dideoxy-3'-fluoro-5-chlorouridine
5-CHLORO-2',3'-DIDEOXY-3'-FLUORO-URIDINE
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Chemsrc provides 5-Chloro-2',3'-dideoxy-3'-fluoro-uridine(CAS#:119644-22-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of 5-Chloro-2',3'-dideoxy-3'-fluoro-uridine are included as well.>> amp version: 5-Chloro-2',3'-dideoxy-3'-fluoro-uridine

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