1-((2R,5S)-5-((tert-butyldimethylsilyloxy)methyl)-2,5-dihydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

Modify Date: 2024-01-08 09:35:47

1-((2R,5S)-5-((tert-butyldimethylsilyloxy)methyl)-2,5-dihydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione Structure
1-((2R,5S)-5-((tert-butyldimethylsilyloxy)methyl)-2,5-dihydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione structure
Common Name 1-((2R,5S)-5-((tert-butyldimethylsilyloxy)methyl)-2,5-dihydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
CAS Number 119794-49-9 Molecular Weight 324.44800
Density N/A Boiling Point N/A
Molecular Formula C15H24N2O4Si Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name 1-((2R,5S)-5-((tert-butyldimethylsilyloxy)methyl)-2,5-dihydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C15H24N2O4Si
Molecular Weight 324.44800
Exact Mass 324.15100
PSA 73.32000
LogP 2.01200

 Synthetic Route

~87%

1-((2R,5S)-5-((tert-butyldimethylsilyloxy)methyl)-2,5-dihydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione Structure

1-((2R,5S)-5-((...

CAS#:119794-49-9

Literature: Nguyen, Corinne; Kasinathan, Ganasan; Leal-Cortijo, Isabel; Musso-Buendia, Alexander; Kaiser, Marcel; Brun, Reto; Ruiz-Perez, Luis M.; Johansson, Nils G.; Gonzalez-Pacanowska, Dolores; Gilbert, Ian H. Journal of Medicinal Chemistry, 2005 ,  vol. 48,  # 19  p. 5942 - 5954

~89%

1-((2R,5S)-5-((tert-butyldimethylsilyloxy)methyl)-2,5-dihydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione Structure

1-((2R,5S)-5-((...

CAS#:119794-49-9

Literature: Chu; Bhadti; Doboszewski; Gu; Kosugi; Pullaiah; Van Roey Journal of Organic Chemistry, 1989 ,  vol. 54,  # 9  p. 2217 - 2225

 Synonyms

5'-O-(tert-butyldimethylsilyl)-2',3'-didehydro-2',3'-dideoxyuridine
.5'-O-TBDMS-2',3'-didehydro-2',3'-dideoxyuridine